Outcome of invasive mechanical ventilation after pediatric allogeneic hematopoietic SCT: results from a prospective, multicenter registry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F14%3A10293073" target="_blank" >RIV/00064203:_____/14:10293073 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/14:10293073

Výsledek na webu

<a href="http://dx.doi.org/10.1038/bmt.2014.147" target="_blank" >http://dx.doi.org/10.1038/bmt.2014.147</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/bmt.2014.147" target="_blank" >10.1038/bmt.2014.147</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Outcome of invasive mechanical ventilation after pediatric allogeneic hematopoietic SCT: results from a prospective, multicenter registry

Popis výsledku v původním jazyce

Exact data on prognosis of children receiving invasive mechanical ventilation (IMV) after allogeneic hematopoietic SCT (HSCT) is lacking. We therefore started a prospective registry in four European university HSCT centers (Leiden, Paris, Prague and Utrecht) and their pediatric intensive care units (PICUs). The registry started in January 2009. In January 2013, the four centers together had treated a total of 83 admissions with IMV. The case fatality rate in these patients was 52%. Mortality 6 months after PICU discharge was 45%. There were significant differences between centers in the proportion of children who received IMV after HSCT (6-23%, P < 0.01), in severity of disease on admission to PICU (predicted mortality 14-37%, P < 0.01), in applying noninvasive ventilation before IMV (3-75% of admissions, P < 0.01) and in the use of renal replacement therapy (RRT) (8-58% of admissions, P < 0.01). Severe impairment in oxygenation, use of RRT and CMV viremia were independent predictors o

Název v anglickém jazyce

Outcome of invasive mechanical ventilation after pediatric allogeneic hematopoietic SCT: results from a prospective, multicenter registry

Popis výsledku anglicky

Exact data on prognosis of children receiving invasive mechanical ventilation (IMV) after allogeneic hematopoietic SCT (HSCT) is lacking. We therefore started a prospective registry in four European university HSCT centers (Leiden, Paris, Prague and Utrecht) and their pediatric intensive care units (PICUs). The registry started in January 2009. In January 2013, the four centers together had treated a total of 83 admissions with IMV. The case fatality rate in these patients was 52%. Mortality 6 months after PICU discharge was 45%. There were significant differences between centers in the proportion of children who received IMV after HSCT (6-23%, P < 0.01), in severity of disease on admission to PICU (predicted mortality 14-37%, P < 0.01), in applying noninvasive ventilation before IMV (3-75% of admissions, P < 0.01) and in the use of renal replacement therapy (RRT) (8-58% of admissions, P < 0.01). Severe impairment in oxygenation, use of RRT and CMV viremia were independent predictors o

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Bone Marrow Transplantation

ISSN

0268-3369

e-ISSN

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Svazek periodika

49

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

1287-1292

Kód UT WoS článku

000343660300007

EID výsledku v databázi Scopus

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