High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature

Kód výsledku v IS VaVaI

RIV/00064203:_____/16:10333629 - isvavai.cz

Nalezeny alternativní kódy

RIV/00216208:11130/16:10333629 RIV/61989592:15110/16:33161883 RIV/00098892:_____/16:N0000083

Výsledek na webu

http://dx.doi.org/10.5507/bp.2016.045

DOI - Digital Object Identifier

10.5507/bp.2016.045

Jazyk výsledku

angličtina

Název v původním jazyce

High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature

Popis výsledku v původním jazyce

Background. Bladder cancer is relatively common in adults. In children, it is extremely rare and in the majority of cases, low grade, low stage urothelial cancers are found. Case report. We describe the diagnostic, therapeutic, and follow-up management of bladder cancer in a 3-year-old boy examined for painless hematuria. Transurethral resection of the tumor was performed and T1 high grade urothelial cancer with osseous metaplasia was found in definitive specimens. During the 2-year follow-up, there has been no recurrence. Typical characteristics of the most prevalent bladder tumors are presented. Conclusion. Despite its low incidence and low prevalence bladder cancer in children is a very serious condition which must not be missed in the differential diagnosis of hematuria or urinary tract infection. It is vital to differentiate urothelial cancer from hamartoma and nephrogenic adenoma and, particularly in osseous metaplasia, from sarcomatoid carcinoma. Especially in high-grade cancers, precise TUR of the tumor with a careful follow-up is essential to detect cancer recurrence and reduce progression. (C) 2016, PALACKY UNIV. All rights reserved.

Název v anglickém jazyce

High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature

Popis výsledku anglicky

Background. Bladder cancer is relatively common in adults. In children, it is extremely rare and in the majority of cases, low grade, low stage urothelial cancers are found. Case report. We describe the diagnostic, therapeutic, and follow-up management of bladder cancer in a 3-year-old boy examined for painless hematuria. Transurethral resection of the tumor was performed and T1 high grade urothelial cancer with osseous metaplasia was found in definitive specimens. During the 2-year follow-up, there has been no recurrence. Typical characteristics of the most prevalent bladder tumors are presented. Conclusion. Despite its low incidence and low prevalence bladder cancer in children is a very serious condition which must not be missed in the differential diagnosis of hematuria or urinary tract infection. It is vital to differentiate urothelial cancer from hamartoma and nephrogenic adenoma and, particularly in osseous metaplasia, from sarcomatoid carcinoma. Especially in high-grade cancers, precise TUR of the tumor with a careful follow-up is essential to detect cancer recurrence and reduce progression. (C) 2016, PALACKY UNIV. All rights reserved.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Papers

ISSN

1213-8118

e-ISSN

—

Svazek periodika

160

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

578-582

Kód UT WoS článku

000392810500020

EID výsledku v databázi Scopus

2-s2.0-85006325270