Optimal Oxygen Saturation in Extremely Premature Neonates

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F19%3A10394207" target="_blank" >RIV/00064203:_____/19:10394207 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/19:10394207

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Xh1HBMi.sd" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Xh1HBMi.sd</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33549/physiolres.933987" target="_blank" >10.33549/physiolres.933987</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Optimal Oxygen Saturation in Extremely Premature Neonates

Popis výsledku v původním jazyce

So far, great efforts have been made to understand the demands of extremely premature neonates (EPNs&apos;; born before the 28th week of gestation) on postnatal care, including optimal oxygen saturation, that will allow them to survive without disability. A major yet unresolved problem is to find an &quot;optimal range&quot; of their oxygen saturation and to maintain it without drops or increases, i.e., without hypoxia or hyperoxia. The individual sections of this paper deal with the changes of SpO(2) (an estimate of SaO(2) measured by pulse oximetry) that occur before, during, and after premature labor, postnatal factors affecting SpO(2), and especially how to find an acceptable compromise in choosing the most effective and minimally harmful range of SpO(2) for EPNs&apos; with the careful FiO(2) adjustment and continually monitored SpO(2) . At present, the two SpO(2) ranges, narrow (90-94 %) vs. wider (88-94 %), are most discussed. However, the question of how much oxygen is too much or little remains unanswered. There is even a view that there is no uniform optimal SpO(2) range for EPNs, and that each newborn has its own, individually specific range that changes due to its intrinsic and/or extrinsic factors.

Název v anglickém jazyce

Optimal Oxygen Saturation in Extremely Premature Neonates

Popis výsledku anglicky

So far, great efforts have been made to understand the demands of extremely premature neonates (EPNs&apos;; born before the 28th week of gestation) on postnatal care, including optimal oxygen saturation, that will allow them to survive without disability. A major yet unresolved problem is to find an &quot;optimal range&quot; of their oxygen saturation and to maintain it without drops or increases, i.e., without hypoxia or hyperoxia. The individual sections of this paper deal with the changes of SpO(2) (an estimate of SaO(2) measured by pulse oximetry) that occur before, during, and after premature labor, postnatal factors affecting SpO(2), and especially how to find an acceptable compromise in choosing the most effective and minimally harmful range of SpO(2) for EPNs&apos; with the careful FiO(2) adjustment and continually monitored SpO(2) . At present, the two SpO(2) ranges, narrow (90-94 %) vs. wider (88-94 %), are most discussed. However, the question of how much oxygen is too much or little remains unanswered. There is even a view that there is no uniform optimal SpO(2) range for EPNs, and that each newborn has its own, individually specific range that changes due to its intrinsic and/or extrinsic factors.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physiological Research

ISSN

0862-8408

e-ISSN

—

Svazek periodika

68

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

171-178

Kód UT WoS článku

000465948800005

EID výsledku v databázi Scopus

2-s2.0-85065489925