Prospective observational study to evaluate the efficacy and safety of the pollen extract Serelys (R) in the management of women with menopausal symptoms

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F19%3A10394323" target="_blank" >RIV/00064203:_____/19:10394323 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/19:10394323

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=6gJE3PNmPC" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=6gJE3PNmPC</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/09513590.2018.1538347" target="_blank" >10.1080/09513590.2018.1538347</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Prospective observational study to evaluate the efficacy and safety of the pollen extract Serelys (R) in the management of women with menopausal symptoms

Popis výsledku v původním jazyce

Safety concerns or contraindications to the use of hormones have resulted in a rise of the use of herbal medicinal products for the management of menopausal symptoms. The pollen extract SerelysA (R) represents, due to its ingredients and mode of action, a new and innovative alternative for the management of these symptoms. The aim of the present study was to demonstrate the efficacy and safety of SerelysA (R). A prospective, open, observational, and multicentre study was performed on 104 menopausal women. The patients received over 3 months the pollen extract SerelysA (R) containing the extracts PI82 and GC Fem in a dosage of twice 160 mg extract and 5 mg vitamin E. Using a validated menopausal rating score, the improvement of menopausal symptoms was recorded. A significant decrease of different menopausal symptoms was observed between the starting point of the study and after 12 weeks (p &lt; .0001). Hot flashes were reduced by 48.5%, sleep disturbance by 50.1%, depressive mood by 51.2%, irritability by 47.9%, fatigue by 47.8%, vaginal dryness by 39.63% and muscles and joint pain by 27.4%. The pollen extract SerelysA (R) reduced significant menopausal symptoms showing a very low side effect profile.

Název v anglickém jazyce

Prospective observational study to evaluate the efficacy and safety of the pollen extract Serelys (R) in the management of women with menopausal symptoms

Popis výsledku anglicky

Safety concerns or contraindications to the use of hormones have resulted in a rise of the use of herbal medicinal products for the management of menopausal symptoms. The pollen extract SerelysA (R) represents, due to its ingredients and mode of action, a new and innovative alternative for the management of these symptoms. The aim of the present study was to demonstrate the efficacy and safety of SerelysA (R). A prospective, open, observational, and multicentre study was performed on 104 menopausal women. The patients received over 3 months the pollen extract SerelysA (R) containing the extracts PI82 and GC Fem in a dosage of twice 160 mg extract and 5 mg vitamin E. Using a validated menopausal rating score, the improvement of menopausal symptoms was recorded. A significant decrease of different menopausal symptoms was observed between the starting point of the study and after 12 weeks (p &lt; .0001). Hot flashes were reduced by 48.5%, sleep disturbance by 50.1%, depressive mood by 51.2%, irritability by 47.9%, fatigue by 47.8%, vaginal dryness by 39.63% and muscles and joint pain by 27.4%. The pollen extract SerelysA (R) reduced significant menopausal symptoms showing a very low side effect profile.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Gynecological Endocrinology

ISSN

0951-3590

e-ISSN

—

Svazek periodika

35

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

4

Strana od-do

360-363

Kód UT WoS článku

000465210500020

EID výsledku v databázi Scopus

2-s2.0-85061446163