Hypoglycemia in the elderly: Watch for atypical symptoms

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F19%3A10410391" target="_blank" >RIV/00064203:_____/19:10410391 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/19:10410391

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=eRS6FrmmNv" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=eRS6FrmmNv</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Hypoglycemia in the elderly: Watch for atypical symptoms

Popis výsledku v původním jazyce

We read with interest the review article by Keber and Fiebert, &quot;Diabetes in the elderly: Matching meds to needs&quot; (J Fam Pract. 2018;67:408-410,412-415). The authors have provided a timely overview of antidiabetes medications for elderly people with type 2 diabetes mellitus (T2DM) and their relative risks for hypoglycemia. We&apos;d like to add to this important conversation. Aging, per se, modifies the glycemic thresholds for autonomic symptoms and cognitive impairment; in older nondiabetic men (mean + SD: age 65 +- 3 years), autonomic symptoms and cognitive dysfunction commence at identical glycemic thresholds (3 +- 0.2 mmol/L [54 +- 4 mg/dL]). By contrast, in younger men (age 23 +- 2 years), a significant gap is observed between the glycemic threshold for symptom generation (3.6 mmol/L [65 mg/dL]) and the onset of cognitive dysfunction (2.6 mmol/L [47 mg/dL]).1,2 The simultaneous occurrence of symptoms and cognitive impairment in older people may adversely affect their ability to recognize and treat hypoglycemia promptly. In addition, hypoglycemia in older T2DM patients often presents with atypical neurologic symptoms, including incoordination and ataxia, slurring of speech, and visual disturbances, which either are not identified as hypoglycemia or are misdiagnosed as other medical disorders (eg, transient ischemic attack).3 Knowledge about hypoglycemia symptoms is poor, in both elderly people with diabetes and their relatives and caregivers, which compromises the ability to identify hypoglycemia and provide effective treatment.4 Education about the possible presentations of hypoglycemia and its effective treatment is essential for older patients and their relatives.

Název v anglickém jazyce

Hypoglycemia in the elderly: Watch for atypical symptoms

Popis výsledku anglicky

We read with interest the review article by Keber and Fiebert, &quot;Diabetes in the elderly: Matching meds to needs&quot; (J Fam Pract. 2018;67:408-410,412-415). The authors have provided a timely overview of antidiabetes medications for elderly people with type 2 diabetes mellitus (T2DM) and their relative risks for hypoglycemia. We&apos;d like to add to this important conversation. Aging, per se, modifies the glycemic thresholds for autonomic symptoms and cognitive impairment; in older nondiabetic men (mean + SD: age 65 +- 3 years), autonomic symptoms and cognitive dysfunction commence at identical glycemic thresholds (3 +- 0.2 mmol/L [54 +- 4 mg/dL]). By contrast, in younger men (age 23 +- 2 years), a significant gap is observed between the glycemic threshold for symptom generation (3.6 mmol/L [65 mg/dL]) and the onset of cognitive dysfunction (2.6 mmol/L [47 mg/dL]).1,2 The simultaneous occurrence of symptoms and cognitive impairment in older people may adversely affect their ability to recognize and treat hypoglycemia promptly. In addition, hypoglycemia in older T2DM patients often presents with atypical neurologic symptoms, including incoordination and ataxia, slurring of speech, and visual disturbances, which either are not identified as hypoglycemia or are misdiagnosed as other medical disorders (eg, transient ischemic attack).3 Knowledge about hypoglycemia symptoms is poor, in both elderly people with diabetes and their relatives and caregivers, which compromises the ability to identify hypoglycemia and provide effective treatment.4 Education about the possible presentations of hypoglycemia and its effective treatment is essential for older patients and their relatives.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30202 - Endocrinology and metabolism (including diabetes, hormones)

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Family Practice

ISSN

0094-3509

e-ISSN

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Svazek periodika

68

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

1

Strana od-do

116

Kód UT WoS článku

000461299600008

EID výsledku v databázi Scopus

2-s2.0-85063517066