Gynecological aspects that may affect the risk of preterm birth and the success of embryo transfers after uterus transplantation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F24%3A10490647" target="_blank" >RIV/00064203:_____/24:10490647 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/24:10490647

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=WULw0HoHcs" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=WULw0HoHcs</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.48095/cccg2024493" target="_blank" >10.48095/cccg2024493</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Gynecological aspects that may affect the risk of preterm birth and the success of embryo transfers after uterus transplantation

Popis výsledku v původním jazyce

Absolute uterine factor infertility is conditioned by the congenital or acquired absence of the uterus or the presence of a nonfunctioning uterus in women who wish to become bio logical mothers. Uterine transplantation along with assisted reproductive techniques can provide this option for women without a uterus. In the early research period, to minimize the risk of preterm birth and other pregnancy-related complications, the uterus of a donor with a history of one to three successfully completed pregnancies was recommended for transplantation. We believe that insisting on a singleton pregnancy is necessary to reduce the risk of premature birth in uterus recipients, rather than insisting on donating a uterus from a woman with a history of at least one birth. Mild post-transplant narrowing of the vaginal-neovaginal anastomosis was expected; however, the fi rst severe vaginal stricture revealed soon after transplantation was an unpleasant surprise. To prevent post-transplant vaginal stricture, gynecologic surgeons should evaluate the shape and size of the donor&apos;s cervix, compare it with the size of the recipient&apos;s neovagina and vaginal vault, and perform a vaginal-neovaginal anastomosis to ensure free access for post-transplant cervical bio psies to reveal signs of subclinical rejection and smooth insertion of the embryo transfer catheter into the uterine cavity.

Název v anglickém jazyce

Gynecological aspects that may affect the risk of preterm birth and the success of embryo transfers after uterus transplantation

Popis výsledku anglicky

Absolute uterine factor infertility is conditioned by the congenital or acquired absence of the uterus or the presence of a nonfunctioning uterus in women who wish to become bio logical mothers. Uterine transplantation along with assisted reproductive techniques can provide this option for women without a uterus. In the early research period, to minimize the risk of preterm birth and other pregnancy-related complications, the uterus of a donor with a history of one to three successfully completed pregnancies was recommended for transplantation. We believe that insisting on a singleton pregnancy is necessary to reduce the risk of premature birth in uterus recipients, rather than insisting on donating a uterus from a woman with a history of at least one birth. Mild post-transplant narrowing of the vaginal-neovaginal anastomosis was expected; however, the fi rst severe vaginal stricture revealed soon after transplantation was an unpleasant surprise. To prevent post-transplant vaginal stricture, gynecologic surgeons should evaluate the shape and size of the donor&apos;s cervix, compare it with the size of the recipient&apos;s neovagina and vaginal vault, and perform a vaginal-neovaginal anastomosis to ensure free access for post-transplant cervical bio psies to reveal signs of subclinical rejection and smooth insertion of the embryo transfer catheter into the uterine cavity.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Česká gynekologie

ISSN

1210-7832

e-ISSN

1805-4455

Svazek periodika

89

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

3

Strana od-do

493-495

Kód UT WoS článku

001397103700001

EID výsledku v databázi Scopus

2-s2.0-85215356630