Prevalence of GBV-c/HGV in HIV-infected patients and potential influence of coinfection on the course of the disease./Prevalence GBV-c/HGV u HIV infikovaných pacientů a možný význam koinfekce pro vývoj nemoci

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F04%3A00011348" target="_blank" >RIV/00064211:_____/04:00011348 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Prevalence of GBV-c/HGV in HIV-infected patients and potential influence of coinfection on the course of the disease.

Popis výsledku v původním jazyce

Objectives: Assessment of prevalence of GBV-c/HGV infection in HIV-infected patients and evaluating of a possible influence of GBV-c/HGV on the course of HIV infection by assessment of immunological and virological markers of progression of HIV infection. Methods: We have investigated seras of 273 HIV-infected patients from AIDS Center of the University Hospital Na Bulovce Prague during 2002-2003. Our target was to assess the presence of markers of GBV-c/HGV infection by semiquantitative HGV PCR evaluation and anti-E2 antibodies by ELISA testing. 271 of serum samples were tested for HGV PCR and 269 samples were tested for anti-E2 antibodies. HIV viral load and CD4 count were tested concurrently. We used Spearman´s test to rule out the dependency of CD4count and HIV viral load on HGV infection. Results: 89 (33,3%) of patients were positive in PCR HGV test and 101 (38,5%) of patients were positive in anti E2-ELISA. No statistically significant efect of GBV-c/HGV infection was observed o

Název v anglickém jazyce

Prevalence of GBV-c/HGV in HIV-infected patients and potential influence of coinfection on the course of the disease.

Popis výsledku anglicky

Objectives: Assessment of prevalence of GBV-c/HGV infection in HIV-infected patients and evaluating of a possible influence of GBV-c/HGV on the course of HIV infection by assessment of immunological and virological markers of progression of HIV infection. Methods: We have investigated seras of 273 HIV-infected patients from AIDS Center of the University Hospital Na Bulovce Prague during 2002-2003. Our target was to assess the presence of markers of GBV-c/HGV infection by semiquantitative HGV PCR evaluation and anti-E2 antibodies by ELISA testing. 271 of serum samples were tested for HGV PCR and 269 samples were tested for anti-E2 antibodies. HIV viral load and CD4 count were tested concurrently. We used Spearman´s test to rule out the dependency of CD4count and HIV viral load on HGV infection. Results: 89 (33,3%) of patients were positive in PCR HGV test and 101 (38,5%) of patients were positive in anti E2-ELISA. No statistically significant efect of GBV-c/HGV infection was observed o

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FN - Epidemiologie, infekční nemoci a klinická imunologie

OECD FORD obor

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Projekt

<a href="/cs/project/NI7509" target="_blank" >NI7509: Sledování vlivu koinfekce HGV na prognózu pacientů s infekcí HIV</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Microbiology and Infection

ISSN

1198-743X

e-ISSN

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Svazek periodika

10

Číslo periodika v rámci svazku

suppl.3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

1

Strana od-do

157-157

Kód UT WoS článku

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EID výsledku v databázi Scopus

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