Dengue fever in Czech travellers: A 10-year retrospective study in a tertiary care centre

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F16%3AN0000013" target="_blank" >RIV/00064211:_____/16:N0000013 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/27283933:_____/15:N0000061 RIV/00216208:11110/16:10323711 RIV/00216208:11130/16:10323711 RIV/00216208:11120/16:43909981 RIV/75010330:_____/16:00011316

Výsledek na webu

<a href="https://www.ncbi.nlm.nih.gov/pubmed/26159629" target="_blank" >https://www.ncbi.nlm.nih.gov/pubmed/26159629</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.tmaid.2015.06.005" target="_blank" >10.1016/j.tmaid.2015.06.005</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Dengue fever in Czech travellers: A 10-year retrospective study in a tertiary care centre

Popis výsledku v původním jazyce

Background: Dengue fever is a frequent cause of morbidity in travellers. The objective was to describe the epidemiological and clinical characteristics of dengue fever in Czech travellers. Method: This descriptive study includes patients with acute dengue fever diagnosed at Hospital Na Bulovce during 2004-2013. Data were collected and analysed retrospectively. Results: A total of 132 patients (83 males and 49 females) of median age 33 years (IQR 29-40) were included. Diagnosis was established by NS1 antigen detection in 87/107 cases (81.3%) and/or RT-PCR in 50/72 (69.4%) and by serology in 25 cases (18.9%). Dengue was acquired in South-East Asia in 69 cases (52.3%), followed by South Asia (48 cases; 36.3%), Latin America (14; 10.6%) and Sub-Saharan Africa (1; 0.8%). The most frequent symptoms included fever, rash and headache. Initial leukocyte and lymphocyte counts were lower in patients who presented in the early phase (0-4 days), however, platelet count was lower and AST, ALT and LDH activity higher in patients with a longer symptoms duration (>= 5 days). The clinical course was mostly uncomplicated. Conclusions: Dengue fever is becoming a frequent cause of fever in Czech travellers. Clinicians should be familiar with the typical clinical findings and novel diagnostic methods. (C) 2015 Elsevier Ltd. All rights reserved.

Název v anglickém jazyce

Dengue fever in Czech travellers: A 10-year retrospective study in a tertiary care centre

Popis výsledku anglicky

Background: Dengue fever is a frequent cause of morbidity in travellers. The objective was to describe the epidemiological and clinical characteristics of dengue fever in Czech travellers. Method: This descriptive study includes patients with acute dengue fever diagnosed at Hospital Na Bulovce during 2004-2013. Data were collected and analysed retrospectively. Results: A total of 132 patients (83 males and 49 females) of median age 33 years (IQR 29-40) were included. Diagnosis was established by NS1 antigen detection in 87/107 cases (81.3%) and/or RT-PCR in 50/72 (69.4%) and by serology in 25 cases (18.9%). Dengue was acquired in South-East Asia in 69 cases (52.3%), followed by South Asia (48 cases; 36.3%), Latin America (14; 10.6%) and Sub-Saharan Africa (1; 0.8%). The most frequent symptoms included fever, rash and headache. Initial leukocyte and lymphocyte counts were lower in patients who presented in the early phase (0-4 days), however, platelet count was lower and AST, ALT and LDH activity higher in patients with a longer symptoms duration (>= 5 days). The clinical course was mostly uncomplicated. Conclusions: Dengue fever is becoming a frequent cause of fever in Czech travellers. Clinicians should be familiar with the typical clinical findings and novel diagnostic methods. (C) 2015 Elsevier Ltd. All rights reserved.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FN - Epidemiologie, infekční nemoci a klinická imunologie

OECD FORD obor

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Projekt

<a href="/cs/project/NT14072" target="_blank" >NT14072: Prediktivní imunologické markery u pacientů s infekcí virem hepatitidy C</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

TRAVEL MEDICINE AND INFECTIOUS DISEASE

ISSN

1477-8939

e-ISSN

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Svazek periodika

14

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

32-38

Kód UT WoS článku

000370722500010

EID výsledku v databázi Scopus

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