The fertility sparing therapy in ectopic pregnancy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F23%3AW0000045" target="_blank" >RIV/00064211:_____/23:W0000045 - isvavai.cz</a>

Výsledek na webu

<a href="https://dx.doi.org/10.48095/cccg202320" target="_blank" >https://dx.doi.org/10.48095/cccg202320</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.48095/cccg202320" target="_blank" >10.48095/cccg202320</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The fertility sparing therapy in ectopic pregnancy

Popis výsledku v původním jazyce

Objective: A review of current knowledge on the possibilities of fertility sparing therapy in case of ectopic pregnancy. Methods and results: Ectopic pregnancy is defined as implantation of an embryo outside the endometrial cavity, most often in the fallopian tube. This dia gnosis is very common among young women. Ectopic pregnancies can be treated using the following three approaches, which can be combined: expectantly, pharmacologically or surgically. Fertility-sparing salpingostomy may be performed during surgical treatment. Medical (pharmacological) treatment consists in the application of methotrexate with a success rate of 75-96%, depending on the initial level of the free beta subunit of human chorionic gonadotropin (13-hCG). This is a safe treatment with minimal side effects. There is no standardization of the blood 13-hCG level limits or of the size of the ectopic pregnancy mass for choosing expectant, surgical or medical treatment. A considerable increase in the rate of Cesarean sections over the last decades has led to an increase in the occurrence of the implantation of the gestational sac in the hysterotomy scar. There are several options to address this dia gnosis, but none is clearly preferred. This issue is also discussed in the article. Conclusion: The goal of ectopic pregnancy treatment is to choose a safe and effective therapy with a low incidence of side effects and maintaining the maximum fertility of women. Properly set indication criteria are most important when choosing the right option.

Název v anglickém jazyce

The fertility sparing therapy in ectopic pregnancy

Popis výsledku anglicky

Objective: A review of current knowledge on the possibilities of fertility sparing therapy in case of ectopic pregnancy. Methods and results: Ectopic pregnancy is defined as implantation of an embryo outside the endometrial cavity, most often in the fallopian tube. This dia gnosis is very common among young women. Ectopic pregnancies can be treated using the following three approaches, which can be combined: expectantly, pharmacologically or surgically. Fertility-sparing salpingostomy may be performed during surgical treatment. Medical (pharmacological) treatment consists in the application of methotrexate with a success rate of 75-96%, depending on the initial level of the free beta subunit of human chorionic gonadotropin (13-hCG). This is a safe treatment with minimal side effects. There is no standardization of the blood 13-hCG level limits or of the size of the ectopic pregnancy mass for choosing expectant, surgical or medical treatment. A considerable increase in the rate of Cesarean sections over the last decades has led to an increase in the occurrence of the implantation of the gestational sac in the hysterotomy scar. There are several options to address this dia gnosis, but none is clearly preferred. This issue is also discussed in the article. Conclusion: The goal of ectopic pregnancy treatment is to choose a safe and effective therapy with a low incidence of side effects and maintaining the maximum fertility of women. Properly set indication criteria are most important when choosing the right option.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

CESKA GYNEKOLOGIE-CZECH GYNAECOLOGY

ISSN

1210-7832

e-ISSN

1805-4455

Svazek periodika

88

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

20-26

Kód UT WoS článku

000988857100001

EID výsledku v databázi Scopus

2-s2.0-85149427719