Vulvodynia and Muscle Hypoxia: A Critical Correlation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F25%3AW0000009" target="_blank" >RIV/00064211:_____/25:W0000009 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/25:10497340 RIV/00216208:11510/25:10497340

Výsledek na webu

<a href="https://www.actualgyn.com/pdf/en_2025_306.pdf" target="_blank" >https://www.actualgyn.com/pdf/en_2025_306.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Vulvodynia and Muscle Hypoxia: A Critical Correlation

Popis výsledku v původním jazyce

Introduction: Idiopathic vulvodynia is a chronic pain syndrome affecting the vulvar area. It severely affects quality of life. Chronic perineal muscle hypoxia may contribute to persistent pain that is refractory to conventional treatments. In our previous study on acute pain syndrome dyspareunia, we found significantly low pulse oximetry levels in the perigenital area of afflicted women. Aims: Our intention was to compare pulse oximetry saturation (SpO(2)) in women affected by vulvodynia with healthy individuals. Design: A retrospective study design was adopted. Participants: The study included 62 participants, with 31 women in the treatment group and 31 in the control group. The participants were women who participated in our previous study on vulvodynia. Methods: Participants were measured for SpO(2) during their regular examinations. The measurement was performed in the perigenital area, specifically the posterior commissure and the spongiosus muscle. Results: The median SpO(2) was 90% in the treatment group and 92% in the controls. This difference was statistically significant (p < .001). The sample size was statistically adequate. Discussion: We observed clinically significant decreased levels of SpO(2) in women with idiopathic chronic vulvodynia compared to healthy controls. This comparison highlighted significant hypoxia in the perigenital muscles and the perimuscular area (p < .001). These findings enhance our understanding of chronic vulvodynia and may inform treatment strategies.

Název v anglickém jazyce

Vulvodynia and Muscle Hypoxia: A Critical Correlation

Popis výsledku anglicky

Introduction: Idiopathic vulvodynia is a chronic pain syndrome affecting the vulvar area. It severely affects quality of life. Chronic perineal muscle hypoxia may contribute to persistent pain that is refractory to conventional treatments. In our previous study on acute pain syndrome dyspareunia, we found significantly low pulse oximetry levels in the perigenital area of afflicted women. Aims: Our intention was to compare pulse oximetry saturation (SpO(2)) in women affected by vulvodynia with healthy individuals. Design: A retrospective study design was adopted. Participants: The study included 62 participants, with 31 women in the treatment group and 31 in the control group. The participants were women who participated in our previous study on vulvodynia. Methods: Participants were measured for SpO(2) during their regular examinations. The measurement was performed in the perigenital area, specifically the posterior commissure and the spongiosus muscle. Results: The median SpO(2) was 90% in the treatment group and 92% in the controls. This difference was statistically significant (p < .001). The sample size was statistically adequate. Discussion: We observed clinically significant decreased levels of SpO(2) in women with idiopathic chronic vulvodynia compared to healthy controls. This comparison highlighted significant hypoxia in the perigenital muscles and the perimuscular area (p < .001). These findings enhance our understanding of chronic vulvodynia and may inform treatment strategies.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

AKTUALNI GYNEKOLOGIE A PORODNICTVI

ISSN

1803-9588

e-ISSN

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Svazek periodika

17

Číslo periodika v rámci svazku

2025

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

4

Strana od-do

37-40

Kód UT WoS článku

001462527900001

EID výsledku v databázi Scopus

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