Functional outcomes and complications of elbow endoprosthesis reconstruction after tumor resection: insights from a national study at two sarcoma centers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064211%3A_____%2F26%3AW0000033" target="_blank" >RIV/00064211:_____/26:W0000033 - isvavai.cz</a>

Výsledek na webu

<a href="https://dx.doi.org/10.1016/j.jse.2025.05.003" target="_blank" >https://dx.doi.org/10.1016/j.jse.2025.05.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jse.2025.05.003" target="_blank" >10.1016/j.jse.2025.05.003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Functional outcomes and complications of elbow endoprosthesis reconstruction after tumor resection: insights from a national study at two sarcoma centers

Popis výsledku v původním jazyce

Background: Elbow tumors, though rare, pose significant reconstructive challenges due to the joint's complex anatomy and limited soft tissue coverage. This study evaluates the functional outcomes, complications, and implant survival rates of modern-design elbow tumor endoprostheses following resection of distal humerus or proximal ulna tumors. Methods: Conducted across 2 tertiary sarcoma centers, the retrospective study analyzed 18 patients treated from 2014 to 2023. Patients underwent primary surgery with consistent surgical and postoperative protocols. The study evaluated implant survival, complications, and functional outcomes following elbow tumor resection and endoprosthetic reconstruction, using Musculoskeletal Tumor Society score, the Toronto Extremity Salvage Score, and the Modified Elbow Performance Score, and range of motion measurements. Factors influencing implant failure, including resection location, bone length, prosthesis type, allograft use, and fixation method, were also analyzed. Results: Implant survival rates were 94%, 86%, and 65% at 1, 3, and 5 years, respectively, with cemented fixation showing lower survival at 5 years compared to uncemented fixation. Intraoperative complications included 3 transient nerve injuries and one humeral fracture, while postoperative complications, classified by the Henderson system, led to 9 revisions in 7 patients. The mean Musculoskeletal Tumor Society, Toronto Extremity Salvage Score, and Modified Elbow Performance Score scores were 78.7% (23.6 +/- 2.9), 75.4% (+/- 8.9), and 82.2% (+/- 9.4), respectively, with no significant differences between humeral and ulnar resections. Patients achieved a mean maximum elbow flexion of 115.26 +/- 16.8 degrees and an overall mean range of motion exceeding 100 degrees. Conclusion: In this national study, elbow endoprosthetic reconstruction after tumor resection was associated with acceptable functional outcomes and a 65% 5-year implant survival rate, though revision surgery was required in nearly 40% of patients. While permanent neurological deficits were rare, the complication burden underscores the need for cautious patient selection and long-term follow-up. Level of evidence: Level IV; Case Series; Treatment Study (c) 2025 The Author(s). Published by Elsevier Inc. on behalf of Journal of Shoulder and Elbow Surgery Board of Trustees. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Název v anglickém jazyce

Functional outcomes and complications of elbow endoprosthesis reconstruction after tumor resection: insights from a national study at two sarcoma centers

Popis výsledku anglicky

Background: Elbow tumors, though rare, pose significant reconstructive challenges due to the joint's complex anatomy and limited soft tissue coverage. This study evaluates the functional outcomes, complications, and implant survival rates of modern-design elbow tumor endoprostheses following resection of distal humerus or proximal ulna tumors. Methods: Conducted across 2 tertiary sarcoma centers, the retrospective study analyzed 18 patients treated from 2014 to 2023. Patients underwent primary surgery with consistent surgical and postoperative protocols. The study evaluated implant survival, complications, and functional outcomes following elbow tumor resection and endoprosthetic reconstruction, using Musculoskeletal Tumor Society score, the Toronto Extremity Salvage Score, and the Modified Elbow Performance Score, and range of motion measurements. Factors influencing implant failure, including resection location, bone length, prosthesis type, allograft use, and fixation method, were also analyzed. Results: Implant survival rates were 94%, 86%, and 65% at 1, 3, and 5 years, respectively, with cemented fixation showing lower survival at 5 years compared to uncemented fixation. Intraoperative complications included 3 transient nerve injuries and one humeral fracture, while postoperative complications, classified by the Henderson system, led to 9 revisions in 7 patients. The mean Musculoskeletal Tumor Society, Toronto Extremity Salvage Score, and Modified Elbow Performance Score scores were 78.7% (23.6 +/- 2.9), 75.4% (+/- 8.9), and 82.2% (+/- 9.4), respectively, with no significant differences between humeral and ulnar resections. Patients achieved a mean maximum elbow flexion of 115.26 +/- 16.8 degrees and an overall mean range of motion exceeding 100 degrees. Conclusion: In this national study, elbow endoprosthetic reconstruction after tumor resection was associated with acceptable functional outcomes and a 65% 5-year implant survival rate, though revision surgery was required in nearly 40% of patients. While permanent neurological deficits were rare, the complication burden underscores the need for cautious patient selection and long-term follow-up. Level of evidence: Level IV; Case Series; Treatment Study (c) 2025 The Author(s). Published by Elsevier Inc. on behalf of Journal of Shoulder and Elbow Surgery Board of Trustees. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30211 - Orthopaedics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2026

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF SHOULDER AND ELBOW SURGERY

ISSN

1058-2746

e-ISSN

1532-6500

Svazek periodika

35

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

12

Strana od-do

e124-e135

Kód UT WoS článku

001640417600001

EID výsledku v databázi Scopus

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