Residual volumes and final weights in different types of plastic infusion containers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F16%3AN0000010" target="_blank" >RIV/00098892:_____/16:N0000010 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15110/16:33159099

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Residual volumes and final weights in different types of plastic infusion containers

Popis výsledku v původním jazyce

Objective: To compare the residual volumes, the drained volumes, and the final weights of different infusion containers with different volumes and degrees of flexibility. The risk of drug error can be aggravated by a high residual volume remaining in a drained intravenous container. A high residual volume can also increase the final weight of the container after drainage. Methods: A total of 80 infusion containers containing normal saline of four different brands (Viaflo® and Freeflex® flexible bags and KabiPac® and Ecoflac® Plus semi-rigid containers) in two different volumes (250 and 500 ml) were tested. Every container type was tested ten times under closevent conditions. Residual and total drained volumes and weights of drained containers before and after drying were assessed. Results: The residual volume that remained in the intravenous containers tested was lower than 2% of the declared volume, with only one exception (KabiPac Plus® 250 ml), in which the residual volume was higher than 10% of the declared volume. Using gravity drainage, among the 250 ml containers, only one (Viaflo®) reached the full declared total drained volume of 250 ml. By contrast, among the 500 ml containers, only one failed o reach the declared drained volume. There were significant differences in favor of flexible bags in the final weights of containers after drainage, and in one case (250 ml KabiPac® semi-rigid container) the residual volume accounted for more than a half of the final container weight. Conclusion: All four types of containers can be used with the same resulting quality of parenteral treatment. Selection of a specific type of container will be affected primarily by the price (both acquisition and waste disposal costs) and requirements of personnel for handling the container

Název v anglickém jazyce

Residual volumes and final weights in different types of plastic infusion containers

Popis výsledku anglicky

Objective: To compare the residual volumes, the drained volumes, and the final weights of different infusion containers with different volumes and degrees of flexibility. The risk of drug error can be aggravated by a high residual volume remaining in a drained intravenous container. A high residual volume can also increase the final weight of the container after drainage. Methods: A total of 80 infusion containers containing normal saline of four different brands (Viaflo® and Freeflex® flexible bags and KabiPac® and Ecoflac® Plus semi-rigid containers) in two different volumes (250 and 500 ml) were tested. Every container type was tested ten times under closevent conditions. Residual and total drained volumes and weights of drained containers before and after drying were assessed. Results: The residual volume that remained in the intravenous containers tested was lower than 2% of the declared volume, with only one exception (KabiPac Plus® 250 ml), in which the residual volume was higher than 10% of the declared volume. Using gravity drainage, among the 250 ml containers, only one (Viaflo®) reached the full declared total drained volume of 250 ml. By contrast, among the 500 ml containers, only one failed o reach the declared drained volume. There were significant differences in favor of flexible bags in the final weights of containers after drainage, and in one case (250 ml KabiPac® semi-rigid container) the residual volume accounted for more than a half of the final container weight. Conclusion: All four types of containers can be used with the same resulting quality of parenteral treatment. Selection of a specific type of container will be affected primarily by the price (both acquisition and waste disposal costs) and requirements of personnel for handling the container

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/EE2.3.30.0041" target="_blank" >EE2.3.30.0041: Podpora vytváření excelentních výzkumných týmů a intersektorální mobility na Univerzitě Palackého v Olomouci II.</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Pharmacy and Pharmaceutical Sciences

ISSN

0975-1491

e-ISSN

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Svazek periodika

8

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

IN - Indická republika

Počet stran výsledku

4

Strana od-do

293-296

Kód UT WoS článku

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EID výsledku v databázi Scopus

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