Differential Diagnosis of Parotid Gland Tumors: Role of Shear Wave Elastography

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F17%3AN0000137" target="_blank" >RIV/00098892:_____/17:N0000137 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15110/17:73583020

Výsledek na webu

<a href="https://downloads.hindawi.com/journals/bmri/2017/9234672.pdf" target="_blank" >https://downloads.hindawi.com/journals/bmri/2017/9234672.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2017/9234672" target="_blank" >10.1155/2017/9234672</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Differential Diagnosis of Parotid Gland Tumors: Role of Shear Wave Elastography

Popis výsledku v původním jazyce

Aim. To create a predictive score for the discrimination between benign and malignant parotid tumors using elastographic parameters and to compare its sensitivity and specificity with standard ultrasound.Methods. A total of 124 patients with parotid gland lesions for whom surgery was planned were examined using conventional ultrasound, Doppler examination, and shear wave elastography. Results of the examinations were compared with those ones of histology. Results. There were 96 benign and 28 malignant lesions in our cohort. Blurred tumor margin alone proved to be an excellent predictor of malignancy with the sensitivity of 79% and specificity of 97%. Enlarged cervical lymph nodes, tumor vascularisation, microcalcifications presence, homogeneous echogenicity, and bilateral occurrence also discriminated between benign and malignant tumors. However, their inclusion in a predictive model did not improve its performance. Elastographic parameters (the stiffness maxima and minima ratio being the best) also exhibited significant differences between benign and malignant tumors, but again, their inclusion did not significantly improve the predictive power of the blurred margin classifier. Conclusion. Even though elastography satisfactorily distinguishes benign from malignant lesions on its own, it hardly provides any additional value in evaluation of biological character of parotid gland tumors when used as an adjunct to regular ultrasound examination.

Název v anglickém jazyce

Differential Diagnosis of Parotid Gland Tumors: Role of Shear Wave Elastography

Popis výsledku anglicky

Aim. To create a predictive score for the discrimination between benign and malignant parotid tumors using elastographic parameters and to compare its sensitivity and specificity with standard ultrasound.Methods. A total of 124 patients with parotid gland lesions for whom surgery was planned were examined using conventional ultrasound, Doppler examination, and shear wave elastography. Results of the examinations were compared with those ones of histology. Results. There were 96 benign and 28 malignant lesions in our cohort. Blurred tumor margin alone proved to be an excellent predictor of malignancy with the sensitivity of 79% and specificity of 97%. Enlarged cervical lymph nodes, tumor vascularisation, microcalcifications presence, homogeneous echogenicity, and bilateral occurrence also discriminated between benign and malignant tumors. However, their inclusion in a predictive model did not improve its performance. Elastographic parameters (the stiffness maxima and minima ratio being the best) also exhibited significant differences between benign and malignant tumors, but again, their inclusion did not significantly improve the predictive power of the blurred margin classifier. Conclusion. Even though elastography satisfactorily distinguishes benign from malignant lesions on its own, it hardly provides any additional value in evaluation of biological character of parotid gland tumors when used as an adjunct to regular ultrasound examination.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30206 - Otorhinolaryngology

Projekt

<a href="/cs/project/NV16-31881A" target="_blank" >NV16-31881A: Technické aspekty a klinické aplikace ultrasonografické elastografie v oblasti hlavy a krku</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BioMed Research International

ISSN

2314-6133

e-ISSN

2314-6141

Svazek periodika

2017

Číslo periodika v rámci svazku

September

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

9234672

Kód UT WoS článku

000410605300001

EID výsledku v databázi Scopus

2-s2.0-85030544452