Comparison of endoscopic mucosal resection and endoscopic submucosal dissection in the treatment of flat neoplastic lesions in the rectum

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F18%3AN0000024" target="_blank" >RIV/00098892:_____/18:N0000024 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15110/18:73587662

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of endoscopic mucosal resection and endoscopic submucosal dissection in the treatment of flat neoplastic lesions in the rectum

Popis výsledku v původním jazyce

Endoscopic submucosal dissection (ESD) is used for en bloc removal of colorectal lesions > 20 mm. As shown by studies mostly from Japan, ESD is more effective than endoscopic mucosal resection (EMR) in achieving en bloc and R0 resection. Nevertheless, the associated high risk of perforation still prevents the wider use of ESD in the West, including in the Czech Republic. The aim of this study was to compare EMR and ESD for the treatment of rectal superficial neoplastic lesions. Main study outcomes were proportion of en bloc, R0 and curative resections, occurrence of complications, and occurrence of local residual neoplasia. A total of 27 and 30 patients were included in ESD and EMR groups, resp. There were no significant differences in gender, lesion size, and presence of invasive carcinoma between the two groups. En bloc resection was achieved in 21 (78%) vs. 2 (7%; p < 0.005) while perforation not requiring surgery occurred in 3 (11%) vs. 0 (p = 0.099) and local residual neoplasia in 2 (9%) vs. 9 (41%) cases (p = 0,017). No procedure was related to lethality in either group. ESD is a promising method for the treatment of rectal neoplastic lesions.

Název v anglickém jazyce

Comparison of endoscopic mucosal resection and endoscopic submucosal dissection in the treatment of flat neoplastic lesions in the rectum

Popis výsledku anglicky

Endoscopic submucosal dissection (ESD) is used for en bloc removal of colorectal lesions > 20 mm. As shown by studies mostly from Japan, ESD is more effective than endoscopic mucosal resection (EMR) in achieving en bloc and R0 resection. Nevertheless, the associated high risk of perforation still prevents the wider use of ESD in the West, including in the Czech Republic. The aim of this study was to compare EMR and ESD for the treatment of rectal superficial neoplastic lesions. Main study outcomes were proportion of en bloc, R0 and curative resections, occurrence of complications, and occurrence of local residual neoplasia. A total of 27 and 30 patients were included in ESD and EMR groups, resp. There were no significant differences in gender, lesion size, and presence of invasive carcinoma between the two groups. En bloc resection was achieved in 21 (78%) vs. 2 (7%; p < 0.005) while perforation not requiring surgery occurred in 3 (11%) vs. 0 (p = 0.099) and local residual neoplasia in 2 (9%) vs. 9 (41%) cases (p = 0,017). No procedure was related to lethality in either group. ESD is a promising method for the treatment of rectal neoplastic lesions.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

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OECD FORD obor

30219 - Gastroenterology and hepatology

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Gastroenterologie a hepatologie

ISSN

1804-7874

e-ISSN

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Svazek periodika

72

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

193-198

Kód UT WoS článku

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EID výsledku v databázi Scopus

2-s2.0-85050070925