Hybrid esophagectomy for oesophageal cancer: long-term results. A single-centre experience

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F21%3AN0000012" target="_blank" >RIV/00098892:_____/21:N0000012 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15110/21:73611074

Výsledek na webu

<a href="https://www.termedia.pl/Hybrid-esophagectomy-for-oesophageal-cancer-long-term-results-A-single-centre-experience,42,42415,1,1.html" target="_blank" >https://www.termedia.pl/Hybrid-esophagectomy-for-oesophageal-cancer-long-term-results-A-single-centre-experience,42,42415,1,1.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5114/wiitm.2020.100893" target="_blank" >10.5114/wiitm.2020.100893</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Hybrid esophagectomy for oesophageal cancer: long-term results. A single-centre experience

Popis výsledku v původním jazyce

Introduction: The authors report long-term outcomes in patients who received neoadjuvant chemoradiotherapy and consequently underwent hybrid oesophagectomy for oesophageal cancer (OC). Aim: To evaluate long-term outcomes in patients suffering from OC, who underwent hybrid oesophagectomy. Material and methods: Our cohort consisted of patients suffering from OC, who received neoadjuvant chemoradiotherapy. Hybrid esophagectomy was performed 8-10 weeks after oncological treatment. Results: Ninety-four patients underwent surgery for OC from 2011 to 2015. Histology revealed adenocarcinoma in 60.6%, squamous cell carcinoma (SCC) in 36.2%, and other type of cancer in 3.2%. Seventy-three (77.7%) patients with advanced stage (T3-4, N0-2, M0) were indicated to receive neoadjuvant chemoradiotherapy (nCRT). Trans-hiatal hybrid oesophagectomy was performed in 83 (88.3%) patients. Transthoracic hybrid oesophagectomy was performed in 11 (11.7%) patients. Histology of the resected specimens of 18 (24.7%) patients did not reveal OC, i.e. pathological complete response (pCR). In our cohort, we proved an association between occurrence of pCR and age as well as disease-free survival (DFS). The patients who presented with pCR were significantly younger - below 60 years of age (p = 0.017). They also showed significantly higher mean DFS (p = 0.004). Conclusions: Combined oesophagectomy with neoadjuvant chemoradiotherapy results in a better long-term outcome in patients suffering from oesophageal cancer. In our set of patients who underwent hybrid esophagectomy, satisfactory short-term and especially long-term results of surgical treatment for oesophageal cancer were observed.

Název v anglickém jazyce

Hybrid esophagectomy for oesophageal cancer: long-term results. A single-centre experience

Popis výsledku anglicky

Introduction: The authors report long-term outcomes in patients who received neoadjuvant chemoradiotherapy and consequently underwent hybrid oesophagectomy for oesophageal cancer (OC). Aim: To evaluate long-term outcomes in patients suffering from OC, who underwent hybrid oesophagectomy. Material and methods: Our cohort consisted of patients suffering from OC, who received neoadjuvant chemoradiotherapy. Hybrid esophagectomy was performed 8-10 weeks after oncological treatment. Results: Ninety-four patients underwent surgery for OC from 2011 to 2015. Histology revealed adenocarcinoma in 60.6%, squamous cell carcinoma (SCC) in 36.2%, and other type of cancer in 3.2%. Seventy-three (77.7%) patients with advanced stage (T3-4, N0-2, M0) were indicated to receive neoadjuvant chemoradiotherapy (nCRT). Trans-hiatal hybrid oesophagectomy was performed in 83 (88.3%) patients. Transthoracic hybrid oesophagectomy was performed in 11 (11.7%) patients. Histology of the resected specimens of 18 (24.7%) patients did not reveal OC, i.e. pathological complete response (pCR). In our cohort, we proved an association between occurrence of pCR and age as well as disease-free survival (DFS). The patients who presented with pCR were significantly younger - below 60 years of age (p = 0.017). They also showed significantly higher mean DFS (p = 0.004). Conclusions: Combined oesophagectomy with neoadjuvant chemoradiotherapy results in a better long-term outcome in patients suffering from oesophageal cancer. In our set of patients who underwent hybrid esophagectomy, satisfactory short-term and especially long-term results of surgical treatment for oesophageal cancer were observed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30212 - Surgery

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Videosurgery and Other Miniinvasive Techniques

ISSN

1895-4588

e-ISSN

2299-0054

Svazek periodika

16

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

8

Strana od-do

297-304

Kód UT WoS článku

000657512800003

EID výsledku v databázi Scopus

2-s2.0-85108164632