Predictors and characteristics of post-acute COVID-19 syndrome in healthcare workers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F23%3A10157244" target="_blank" >RIV/00098892:_____/23:10157244 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/23:10450070 RIV/61989592:15110/23:73614310

Výsledek na webu

<a href="https://www.tandfonline.com/doi/full/10.1080/23744235.2022.2136750" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/23744235.2022.2136750</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/23744235.2022.2136750" target="_blank" >10.1080/23744235.2022.2136750</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Predictors and characteristics of post-acute COVID-19 syndrome in healthcare workers

Popis výsledku v původním jazyce

Background: Post-acute COVID-19 syndrome (PCS) is a multisystem disorder degrading the quality of life. The study determined characteristics and predictors of PCS in unvaccinated healthcare workers (HCWs) suffering from PCS based on a comparison with their fully recovered counterparts. Methods: 305 HCWs were examined at least 12 weeks post COVID-19 symptom onset to obtain data about their acute phase of COVID-19 and current health status and tested for complete blood count, C-reactive protein (CRP), electrophoresis of plasma proteins and SARS-CoV-2-specific immunoglobulin (Ig) G and M. Results: 181 (59.3%) HCWs reported persisting symptoms attributable to PCS during the examination and 124 (40.7%) HCWs stated no symptoms. In the entire sample, the mean CRP level slightly exceeded the normal range (6.63 mg/L, 95% confidence interval [CI] 5.96–7.3) while all other laboratory results were within the normal range. No statistically significant differences in laboratory results were revealed between both subgroups except for the mean Ig levels, which were higher in HCWs with PCS. The average number of symptoms of PCS was 1.9 (median 2). The most frequent symptoms of PCS were fatigue that interfered with daily life (47.5%), shortness of breath (38.1%), muscle or joint aches (16%), loss of smell (14.9%), headache (14.9%) and sleep disorders (11%). The only statistically significant predictors of PCS were female sex (odds ratio [OR] 1.48, 95% CI 1.059–2.067, p = .022) and increasing age (OR 1.04, 95% CI 1.01–1.07, p = .008). Conclusions: PCS appears to be a prevalent condition determined by female sex and increasing age.

Název v anglickém jazyce

Predictors and characteristics of post-acute COVID-19 syndrome in healthcare workers

Popis výsledku anglicky

Background: Post-acute COVID-19 syndrome (PCS) is a multisystem disorder degrading the quality of life. The study determined characteristics and predictors of PCS in unvaccinated healthcare workers (HCWs) suffering from PCS based on a comparison with their fully recovered counterparts. Methods: 305 HCWs were examined at least 12 weeks post COVID-19 symptom onset to obtain data about their acute phase of COVID-19 and current health status and tested for complete blood count, C-reactive protein (CRP), electrophoresis of plasma proteins and SARS-CoV-2-specific immunoglobulin (Ig) G and M. Results: 181 (59.3%) HCWs reported persisting symptoms attributable to PCS during the examination and 124 (40.7%) HCWs stated no symptoms. In the entire sample, the mean CRP level slightly exceeded the normal range (6.63 mg/L, 95% confidence interval [CI] 5.96–7.3) while all other laboratory results were within the normal range. No statistically significant differences in laboratory results were revealed between both subgroups except for the mean Ig levels, which were higher in HCWs with PCS. The average number of symptoms of PCS was 1.9 (median 2). The most frequent symptoms of PCS were fatigue that interfered with daily life (47.5%), shortness of breath (38.1%), muscle or joint aches (16%), loss of smell (14.9%), headache (14.9%) and sleep disorders (11%). The only statistically significant predictors of PCS were female sex (odds ratio [OR] 1.48, 95% CI 1.059–2.067, p = .022) and increasing age (OR 1.04, 95% CI 1.01–1.07, p = .008). Conclusions: PCS appears to be a prevalent condition determined by female sex and increasing age.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30305 - Occupational health

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Infectious Diseases

ISSN

2374-4235

e-ISSN

2374-4243

Svazek periodika

55

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

125-131

Kód UT WoS článku

000873484100001

EID výsledku v databázi Scopus

2-s2.0-85141015609