COVID-19 reduces cardiorespiratory fitness even months after a mild to moderate acute phase: a retrospective cohort study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F23%3A10157916" target="_blank" >RIV/00098892:_____/23:10157916 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/23:10466157

Výsledek na webu

<a href="https://www.tandfonline.com/doi/full/10.1080/23744235.2023.2228408?scroll=top&needAccess=true&role=tab" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/23744235.2023.2228408?scroll=top&needAccess=true&role=tab</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/23744235.2023.2228408" target="_blank" >10.1080/23744235.2023.2228408</a>

Jazyk výsledku

angličtina

Název v původním jazyce

COVID-19 reduces cardiorespiratory fitness even months after a mild to moderate acute phase: a retrospective cohort study

Popis výsledku v původním jazyce

Background: COVID-19 survivors may experience long-term health problems, including deterioration of cardiorespiratory fitness (CRF), as demonstrated by several cross-sectional studies that compared the results of cardiopulmonary exercise tests (CPET) performed only after COVID-19 with predicted values. This study aimed to analyze a change in CRF between repeated CPETs in response to suffered COVID-19. Methods: A total of 127 healthcare workers (HCWs; mean age 55.7 years) underwent two CPETs with a mean interval of 762 days. Forty HCWs suffered from COVID-19 (mild to moderate severity) in the interim (321 days before the second CPET), and 87 HCWs formed a control group. Mixed-effects regression with multiple adjustment and interaction terms was used for two response variables – maximum oxygen uptake (VO2 max) and power output. Results: Between both CPETs, mean VO2 max decreased statistically significantly in the COVID-19 subgroup (by 3.12 mL/kg/min, p = .034) and insignificantly in controls (by 0.56 mL/kg/min, p = .412). The proportion of HCWs achieving predicted VO2 max decreased from 75.9% to 59.5% (p = .161) in COVID-19 survivors, while it increased from 73.8% to 81% (p = .274) in controls. COVID-19 (β = −0.66, p = .014)) and body mass index (β = −0.49, p &lt; .001) were independent negative predictors of VO2 max change. COVID-19 was not associated with a change in power output. Conclusions: On the basis of repeated CPETs, COVID-19 significantly, albeit rather modestly, reduces CRF almost one year after infection. The reduction persists even after the acute phase with mild or moderate severity.

Název v anglickém jazyce

COVID-19 reduces cardiorespiratory fitness even months after a mild to moderate acute phase: a retrospective cohort study

Popis výsledku anglicky

Background: COVID-19 survivors may experience long-term health problems, including deterioration of cardiorespiratory fitness (CRF), as demonstrated by several cross-sectional studies that compared the results of cardiopulmonary exercise tests (CPET) performed only after COVID-19 with predicted values. This study aimed to analyze a change in CRF between repeated CPETs in response to suffered COVID-19. Methods: A total of 127 healthcare workers (HCWs; mean age 55.7 years) underwent two CPETs with a mean interval of 762 days. Forty HCWs suffered from COVID-19 (mild to moderate severity) in the interim (321 days before the second CPET), and 87 HCWs formed a control group. Mixed-effects regression with multiple adjustment and interaction terms was used for two response variables – maximum oxygen uptake (VO2 max) and power output. Results: Between both CPETs, mean VO2 max decreased statistically significantly in the COVID-19 subgroup (by 3.12 mL/kg/min, p = .034) and insignificantly in controls (by 0.56 mL/kg/min, p = .412). The proportion of HCWs achieving predicted VO2 max decreased from 75.9% to 59.5% (p = .161) in COVID-19 survivors, while it increased from 73.8% to 81% (p = .274) in controls. COVID-19 (β = −0.66, p = .014)) and body mass index (β = −0.49, p &lt; .001) were independent negative predictors of VO2 max change. COVID-19 was not associated with a change in power output. Conclusions: On the basis of repeated CPETs, COVID-19 significantly, albeit rather modestly, reduces CRF almost one year after infection. The reduction persists even after the acute phase with mild or moderate severity.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30303 - Infectious Diseases

Projekt

<a href="/cs/project/NU22-A-105" target="_blank" >NU22-A-105: Prediktivní biomarkery závažnosti a odpovědi na terapii COVID-19</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Infectious Diseases

ISSN

2374-4235

e-ISSN

2374-4243

Svazek periodika

55

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

684-693

Kód UT WoS článku

001021407100001

EID výsledku v databázi Scopus

2-s2.0-85164174482