Direct mailing of HPV self-sampling kits to women aged 50–65 non-participating in cervical screening in the Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F24%3A10158620" target="_blank" >RIV/00098892:_____/24:10158620 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/24:00135936 RIV/00216208:11110/24:10478392 RIV/61989592:15110/24:73625104 RIV/00064165:_____/24:10478392

Výsledek na webu

<a href="https://academic.oup.com/eurpub/article/34/2/361/7542404?login=false" target="_blank" >https://academic.oup.com/eurpub/article/34/2/361/7542404?login=false</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/eurpub/ckad229" target="_blank" >10.1093/eurpub/ckad229</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Direct mailing of HPV self-sampling kits to women aged 50–65 non-participating in cervical screening in the Czech Republic

Popis výsledku v původním jazyce

Background: A population-based cervical cancer screening programme is implemented in the Czech Republic. However, participation is insufficient among women over 50 years. This study aimed to estimate the potential improvement in participation through directly mailed HPV self-sampling kits (HPVssk) compared with standard invitation letters in women aged 50–65 non-participating in screening. Methods: The study recruited 1564 eligible women (no cervical cancer screening in the last 3 years or more, no previous treatment associated with cervical lesions or cervical cancer). Eight hundred women were mailed with an HPVssk (HPVssk group), and 764 women were sent a standard invitation letter (control group) inviting them to a routine screening (Pap test). The primary outcome was a comparison of the overall participation rate between study groups using a binominal regression model. Results: The participation rate in the HPVssk group was 13.4% [95% confidence interval (CI) 11.2–15.9%; 7.4% of women returned the HPVssk and 6.0% attended gynaecological examination] and 5.0% (95% CI 3.6–6.8%) in the control group. Using the binominal regression model, the difference between the groups was estimated as 7.6% (95% CI 5.0–10.2%; P &lt; 0.001). In the HPVssk group, 22% of women who returned HPVssk had a positive result and 70% of them underwent a follow-up examination. Conclusions: Compared with traditional invitation letters, the direct mailing of the HPVssk achieved a significantly higher participation rate, along with a notable HPV positivity rate among HPVssk responders. This approach offers a potentially viable method for engaging women who have not yet attended a cervical screening programme.

Název v anglickém jazyce

Direct mailing of HPV self-sampling kits to women aged 50–65 non-participating in cervical screening in the Czech Republic

Popis výsledku anglicky

Background: A population-based cervical cancer screening programme is implemented in the Czech Republic. However, participation is insufficient among women over 50 years. This study aimed to estimate the potential improvement in participation through directly mailed HPV self-sampling kits (HPVssk) compared with standard invitation letters in women aged 50–65 non-participating in screening. Methods: The study recruited 1564 eligible women (no cervical cancer screening in the last 3 years or more, no previous treatment associated with cervical lesions or cervical cancer). Eight hundred women were mailed with an HPVssk (HPVssk group), and 764 women were sent a standard invitation letter (control group) inviting them to a routine screening (Pap test). The primary outcome was a comparison of the overall participation rate between study groups using a binominal regression model. Results: The participation rate in the HPVssk group was 13.4% [95% confidence interval (CI) 11.2–15.9%; 7.4% of women returned the HPVssk and 6.0% attended gynaecological examination] and 5.0% (95% CI 3.6–6.8%) in the control group. Using the binominal regression model, the difference between the groups was estimated as 7.6% (95% CI 5.0–10.2%; P &lt; 0.001). In the HPVssk group, 22% of women who returned HPVssk had a positive result and 70% of them underwent a follow-up examination. Conclusions: Compared with traditional invitation letters, the direct mailing of the HPVssk achieved a significantly higher participation rate, along with a notable HPV positivity rate among HPVssk responders. This approach offers a potentially viable method for engaging women who have not yet attended a cervical screening programme.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30304 - Public and environmental health

Projekt

<a href="/cs/project/EF16_013%2F0001818" target="_blank" >EF16_013/0001818: Modernizace a podpora výzkumných aktivit národní infrastruktury pro translační medicínu EATRIS-CZ</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Public Health

ISSN

1101-1262

e-ISSN

1464-360X

Svazek periodika

34

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

361-367

Kód UT WoS článku

001147898300001

EID výsledku v databázi Scopus

2-s2.0-85189660731