Effects of exposure to three environmental chemicals on the selected biochemical parameters of the blood plasma of rainbow trout, Oncorhynchus mykiss (Walbaum)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00100595%3A_____%2F16%3AN0000043" target="_blank" >RIV/00100595:_____/16:N0000043 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.degruyter.com/downloadpdf/j/cszma.2016.65.issue-1/cszma-2016-0002/cszma-2016-0002.pdf" target="_blank" >https://www.degruyter.com/downloadpdf/j/cszma.2016.65.issue-1/cszma-2016-0002/cszma-2016-0002.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/cszma-2016-0002" target="_blank" >10.1515/cszma-2016-0002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effects of exposure to three environmental chemicals on the selected biochemical parameters of the blood plasma of rainbow trout, Oncorhynchus mykiss (Walbaum)

Popis výsledku v původním jazyce

Rainbow trout Oncorhynchus mykiss at a weight of 115 ± 24 g (mean ± SD) were experimentally injected with di(2-ethylhexyl)phthalate (DEHP), 2,3,7,8-tetrachlorodibenzo-p-dioxine (TCDD) and gamma isomer of hexachlorocyclohexane (γ-HCH ) to evaluate nitrogen metabolism (total protein [TP], blood urea nitrogen, uric acid [UA], creatinine), carbohydrate metabolism (glucose), mineral metabolism (inorganic phosphate[P], total calcium [Cat]), and catalytic activity of enzymes (alanine aminotransferase [ALT], aspartate aminotransferase [AST], alkaline phosphatase [ALP], lactate dehydrogenase [LD]). After 21 days, the tested xenobiotics, administered by the intraperitoneally route, caused the following effect: in comparison with negative controls, fish injected with DEHP at concentrations of 200 or 50 mg kg-1 of body weight were found to have a higher level of P and lower level of Cat and decreased catalytic concentrations of ALT, AST, ALP and LD in the plasma of the peripheral blood. A higher level of TP and P and a decreased catalytic concentration of ALT were found when TCDD was administered at a dose of 2 μg kg-1. A decrease in the catalytic concentrations of ALT and ALP occurred in fish injected with γ-HCH in a dose of 50 mg kg-1. UA and P levels were decreased in fish injected with γ-HCH in a dose of 5 mg kg-1.

Název v anglickém jazyce

Effects of exposure to three environmental chemicals on the selected biochemical parameters of the blood plasma of rainbow trout, Oncorhynchus mykiss (Walbaum)

Popis výsledku anglicky

Rainbow trout Oncorhynchus mykiss at a weight of 115 ± 24 g (mean ± SD) were experimentally injected with di(2-ethylhexyl)phthalate (DEHP), 2,3,7,8-tetrachlorodibenzo-p-dioxine (TCDD) and gamma isomer of hexachlorocyclohexane (γ-HCH ) to evaluate nitrogen metabolism (total protein [TP], blood urea nitrogen, uric acid [UA], creatinine), carbohydrate metabolism (glucose), mineral metabolism (inorganic phosphate[P], total calcium [Cat]), and catalytic activity of enzymes (alanine aminotransferase [ALT], aspartate aminotransferase [AST], alkaline phosphatase [ALP], lactate dehydrogenase [LD]). After 21 days, the tested xenobiotics, administered by the intraperitoneally route, caused the following effect: in comparison with negative controls, fish injected with DEHP at concentrations of 200 or 50 mg kg-1 of body weight were found to have a higher level of P and lower level of Cat and decreased catalytic concentrations of ALT, AST, ALP and LD in the plasma of the peripheral blood. A higher level of TP and P and a decreased catalytic concentration of ALT were found when TCDD was administered at a dose of 2 μg kg-1. A decrease in the catalytic concentrations of ALT and ALP occurred in fish injected with γ-HCH in a dose of 50 mg kg-1. UA and P levels were decreased in fish injected with γ-HCH in a dose of 5 mg kg-1.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GL - Rybářství

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Musei Silesiae, Scientiae Naturales

ISSN

2336-3193

e-ISSN

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Svazek periodika

65

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

18

Strana od-do

15-32

Kód UT WoS článku

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EID výsledku v databázi Scopus

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