Cardiac autonomic control in Brugada syndrome patients during sleep: The effects of sleep disordered breathing

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F13%3A00060583" target="_blank" >RIV/00159816:_____/13:00060583 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ijcard.2013.04.137" target="_blank" >http://dx.doi.org/10.1016/j.ijcard.2013.04.137</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijcard.2013.04.137" target="_blank" >10.1016/j.ijcard.2013.04.137</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cardiac autonomic control in Brugada syndrome patients during sleep: The effects of sleep disordered breathing

Popis výsledku v původním jazyce

Aims: Brugada syndrome is characterized by typical ECG features, ventricular arrhythmias and sudden cardiac death (SCD), more frequent during nighttime. Autonomic cardiovascular control has been implicated in triggering the ventricular arrhythmias. Sleep-disordered breathing (SDB) elicits marked autonomic changes during sleep and is also associated with an increased risk of nighttime SCD. Brugada patients may have a higher likelihood of SDB compared to controls. However, no data are available on cardiacautonomic control in Brugada patients, particularly with regard to the comorbidity of SDB. Methods: We evaluated autonomic cardiovascular control in Brugada patients with SDB (BRU-SDB, n = 9), without SDB (BRU, n = 9), in controls (CON, n = 8) and in non-Brugada patients with SDB (n = 6), during wakefulness and sleep (N2, N3 and REM). Linear spectral and entropy-derived measures of heart rate variability (HRV) were performed during apnea-free stable breathing epochs. Results: Total HRV

Název v anglickém jazyce

Cardiac autonomic control in Brugada syndrome patients during sleep: The effects of sleep disordered breathing

Popis výsledku anglicky

Aims: Brugada syndrome is characterized by typical ECG features, ventricular arrhythmias and sudden cardiac death (SCD), more frequent during nighttime. Autonomic cardiovascular control has been implicated in triggering the ventricular arrhythmias. Sleep-disordered breathing (SDB) elicits marked autonomic changes during sleep and is also associated with an increased risk of nighttime SCD. Brugada patients may have a higher likelihood of SDB compared to controls. However, no data are available on cardiacautonomic control in Brugada patients, particularly with regard to the comorbidity of SDB. Methods: We evaluated autonomic cardiovascular control in Brugada patients with SDB (BRU-SDB, n = 9), without SDB (BRU, n = 9), in controls (CON, n = 8) and in non-Brugada patients with SDB (n = 6), during wakefulness and sleep (N2, N3 and REM). Linear spectral and entropy-derived measures of heart rate variability (HRV) were performed during apnea-free stable breathing epochs. Results: Total HRV

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International journal of cardiology

ISSN

0167-5273

e-ISSN

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Svazek periodika

168

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

6

Strana od-do

3267-3272

Kód UT WoS článku

000326219600030

EID výsledku v databázi Scopus

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