Role of Preexisting Disability in Patients Treated With Intravenous Thrombolysis for Ischemic Stroke
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F14%3A00060745" target="_blank" >RIV/00159816:_____/14:00060745 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1161/STROKEAHA.113.003744" target="_blank" >http://dx.doi.org/10.1161/STROKEAHA.113.003744</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1161/STROKEAHA.113.003744" target="_blank" >10.1161/STROKEAHA.113.003744</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Role of Preexisting Disability in Patients Treated With Intravenous Thrombolysis for Ischemic Stroke
Popis výsledku v původním jazyce
Background and Purpose Little is known about the effect of thrombolysis in patients with preexisting disability. Our aim was to evaluate the impact of different levels of prestroke disability on patients' profile and outcome after intravenous thrombolysis. Methods We analyzed the data of all stroke patients admitted between October 2003 and December 2011 that were contributed to the Safe Implementation of Treatments in Stroke-Eastern Europe (SITS-EAST) registry. Patients with no prestroke disability atall (modified Rankin Scale [mRS] score, 0) were used as a reference in multivariable logistic regression. Results Of 7250 patients, 5995 (82%) had prestroke mRS 0, 791 (11%) had prestroke mRS 1, 293 (4%) had prestroke mRS 2, and 171 (2%) had prestroke mRS 3. Compared with patients with mRS 0, all other groups were older, had more comorbidities, and more severe neurological deficit on admission. There was no clear association between preexisting disability and the risk of symptomatic intr
Název v anglickém jazyce
Role of Preexisting Disability in Patients Treated With Intravenous Thrombolysis for Ischemic Stroke
Popis výsledku anglicky
Background and Purpose Little is known about the effect of thrombolysis in patients with preexisting disability. Our aim was to evaluate the impact of different levels of prestroke disability on patients' profile and outcome after intravenous thrombolysis. Methods We analyzed the data of all stroke patients admitted between October 2003 and December 2011 that were contributed to the Safe Implementation of Treatments in Stroke-Eastern Europe (SITS-EAST) registry. Patients with no prestroke disability atall (modified Rankin Scale [mRS] score, 0) were used as a reference in multivariable logistic regression. Results Of 7250 patients, 5995 (82%) had prestroke mRS 0, 791 (11%) had prestroke mRS 1, 293 (4%) had prestroke mRS 2, and 171 (2%) had prestroke mRS 3. Compared with patients with mRS 0, all other groups were older, had more comorbidities, and more severe neurological deficit on admission. There was no clear association between preexisting disability and the risk of symptomatic intr
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FH - Neurologie, neurochirurgie, neurovědy
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: Fakultní nemocnice u sv. Anny v Brně - Mezinárodní centrum klinického výzkumu (FNUSA - ICRC)</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Stroke
ISSN
0039-2499
e-ISSN
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Svazek periodika
45
Číslo periodika v rámci svazku
3
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
6
Strana od-do
770-775
Kód UT WoS článku
000331876800037
EID výsledku v databázi Scopus
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