Modulation of Endothelial Glycocalyx Structure under Inflammatory Conditions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F14%3A00061023" target="_blank" >RIV/00159816:_____/14:00061023 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081707:_____/14:00435406 RIV/00216224:14310/14:00107105

Výsledek na webu

<a href="http://www.hindawi.com/journals/mi/2014/694312/" target="_blank" >http://www.hindawi.com/journals/mi/2014/694312/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2014/694312" target="_blank" >10.1155/2014/694312</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Modulation of Endothelial Glycocalyx Structure under Inflammatory Conditions

Popis výsledku v původním jazyce

The glycocalyx of the endothelium is an intravascular compartment that creates a barrier between circulating blood and the vessel wall. The glycocalyx is suggested to play an important role in numerous physiological processes including the regulation ofvascular permeability, the prevention of the margination of blood cells to the vessel wall, and the transmission of shear stress. Various theoretical models and experimental approaches provide data about changes to the structure and functions of the glycocalyx under various types of inflammatory conditions. These alterations are suggested to promote inflammatory processes in vessels and contribute to the pathogenesis of number of diseases. In this review we summarize current knowledge about the modulation of the glycocalyx under inflammatory conditions and the consequences for the course of inflammation in vessels. The structure and functions of endothelial glycocalyx are briefly discussed in the context of methodological approaches reg

Název v anglickém jazyce

Modulation of Endothelial Glycocalyx Structure under Inflammatory Conditions

Popis výsledku anglicky

The glycocalyx of the endothelium is an intravascular compartment that creates a barrier between circulating blood and the vessel wall. The glycocalyx is suggested to play an important role in numerous physiological processes including the regulation ofvascular permeability, the prevention of the margination of blood cells to the vessel wall, and the transmission of shear stress. Various theoretical models and experimental approaches provide data about changes to the structure and functions of the glycocalyx under various types of inflammatory conditions. These alterations are suggested to promote inflammatory processes in vessels and contribute to the pathogenesis of number of diseases. In this review we summarize current knowledge about the modulation of the glycocalyx under inflammatory conditions and the consequences for the course of inflammation in vessels. The structure and functions of endothelial glycocalyx are briefly discussed in the context of methodological approaches reg

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EC - Imunologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Mediators of Inflammation

ISSN

0962-9351

e-ISSN

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Svazek periodika

2014

Číslo periodika v rámci svazku

2014

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

17

Strana od-do

694312

Kód UT WoS článku

000334284300001

EID výsledku v databázi Scopus

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