Statins and Vascular Dementia: A Review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F14%3A00061137" target="_blank" >RIV/00159816:_____/14:00061137 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.3233/JAD-132366" target="_blank" >http://dx.doi.org/10.3233/JAD-132366</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3233/JAD-132366" target="_blank" >10.3233/JAD-132366</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Statins and Vascular Dementia: A Review

Popis výsledku v původním jazyce

The impact of statin therapy on dementia has been a hot topic of debate over the last decade and still remains highly controversial. Among all causes of dementia, vascular dementia (VaD) is the one type that is more likely to benefit from statins. To date no randomized clinical trials have been published and no systematic review has investigated a possible preventive effect of statins on the VaD subtype. In the present literature review, we tried to identify all available data on the effect of statins specifically in patients with VaD, and to further discuss this possible association. Our literature search highlighted two cross-sectional studies, two prospective cohort studies, and one retrospective cohort study. Two of the studies found a significantpositive effect of statin treatment on VaD, depicted by the lower incidence of VaD in statin users, while the others reported non-significant associations. The relatively small numbers of VaD patients and statin users, as well as the pres

Název v anglickém jazyce

Statins and Vascular Dementia: A Review

Popis výsledku anglicky

The impact of statin therapy on dementia has been a hot topic of debate over the last decade and still remains highly controversial. Among all causes of dementia, vascular dementia (VaD) is the one type that is more likely to benefit from statins. To date no randomized clinical trials have been published and no systematic review has investigated a possible preventive effect of statins on the VaD subtype. In the present literature review, we tried to identify all available data on the effect of statins specifically in patients with VaD, and to further discuss this possible association. Our literature search highlighted two cross-sectional studies, two prospective cohort studies, and one retrospective cohort study. Two of the studies found a significantpositive effect of statin treatment on VaD, depicted by the lower incidence of VaD in statin users, while the others reported non-significant associations. The relatively small numbers of VaD patients and statin users, as well as the pres

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: Fakultní nemocnice u sv. Anny v Brně - Mezinárodní centrum klinického výzkumu (FNUSA - ICRC)</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Alzheimers Disease

ISSN

1387-2877

e-ISSN

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Svazek periodika

42

Číslo periodika v rámci svazku

S3

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

"S315"-"S320"

Kód UT WoS článku

000341595800033

EID výsledku v databázi Scopus

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