Blood Glucose, Diet-Based Glycemic Load and Cognitive Aging Among Dementia-Free Older Adults

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00061182" target="_blank" >RIV/00159816:_____/15:00061182 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1093/gerona/glu135" target="_blank" >http://dx.doi.org/10.1093/gerona/glu135</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/gerona/glu135" target="_blank" >10.1093/gerona/glu135</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Blood Glucose, Diet-Based Glycemic Load and Cognitive Aging Among Dementia-Free Older Adults

Popis výsledku v původním jazyce

BACKGROUND: Although evidence indicates that Type II Diabetes is related to abnormal brain aging, the influence of elevated blood glucose on long-term cognitive change is unclear. In addition, the relationship between diet-based glycemic load and cognitive aging has not been extensively studied. The focus of this study was to investigate the influence of diet-based glycemic load and blood glucose on cognitive aging in older adults followed for up to 16 years. METHODS: Eight-hundred and thirty-eight cognitively healthy adults aged GREATER-THAN OR EQUAL TO50 years (M = 63.1, SD = 8.3) from the Swedish Adoption/Twin Study of Aging were studied. Mixed effects growth models were utilized to assess overall performance and change in general cognitive functioning, perceptual speed, memory, verbal ability, and spatial ability as a function of baseline blood glucose and diet-based glycemic load. RESULTS: High blood glucose was related to poorer overall performance on perceptual speed as well as

Název v anglickém jazyce

Blood Glucose, Diet-Based Glycemic Load and Cognitive Aging Among Dementia-Free Older Adults

Popis výsledku anglicky

BACKGROUND: Although evidence indicates that Type II Diabetes is related to abnormal brain aging, the influence of elevated blood glucose on long-term cognitive change is unclear. In addition, the relationship between diet-based glycemic load and cognitive aging has not been extensively studied. The focus of this study was to investigate the influence of diet-based glycemic load and blood glucose on cognitive aging in older adults followed for up to 16 years. METHODS: Eight-hundred and thirty-eight cognitively healthy adults aged GREATER-THAN OR EQUAL TO50 years (M = 63.1, SD = 8.3) from the Swedish Adoption/Twin Study of Aging were studied. Mixed effects growth models were utilized to assess overall performance and change in general cognitive functioning, perceptual speed, memory, verbal ability, and spatial ability as a function of baseline blood glucose and diet-based glycemic load. RESULTS: High blood glucose was related to poorer overall performance on perceptual speed as well as

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: Fakultní nemocnice u sv. Anny v Brně - Mezinárodní centrum klinického výzkumu (FNUSA - ICRC)</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journals of gerontology series A : Biological sciences and medical sciences

ISSN

1079-5006

e-ISSN

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Svazek periodika

70

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

471-479

Kód UT WoS článku

000353896100009

EID výsledku v databázi Scopus

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