Chlorella pyrenoidosa, young barley and fruit peel polyphenols in rat breast cancer model - the effects on plasma lipid metabolism
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00063193" target="_blank" >RIV/00159816:_____/15:00063193 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1515/biolog-2015-0025" target="_blank" >http://dx.doi.org/10.1515/biolog-2015-0025</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1515/biolog-2015-0025" target="_blank" >10.1515/biolog-2015-0025</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Chlorella pyrenoidosa, young barley and fruit peel polyphenols in rat breast cancer model - the effects on plasma lipid metabolism
Popis výsledku v původním jazyce
On the basis of several preclinical and clinical studies, we have assumed that phytochemicals may play an important role in plasma lipid metabolism. The aim of this study was to evaluate the effects of dietary administered Chlorella pyrenoidosa, young barley and fruit peel polyphenols from Flavin7 on plasma lipid metabolism in breast cancer model in female rats. The phytopharmaceuticals were dietary administered at two different concentrations (0.3% and 3%). The administration of drugs lasted for the whole duration of the experiment (14-15 weeks) until autopsy. At the end of the experiments blood was collected from animals and serum lipid parameters were evaluated. Flavin7 in lower dose significantly decreased LDL-cholesterol and in higher dose significantly decreased triacylglycerol and VLDL-cholesterol levels. Chlorella at the higher dose significantly decreased LDL-and VLDL-cholesterol and triacylglycerol levels. Young barley significantly decreased LDL cholesterol (at the higher do
Název v anglickém jazyce
Chlorella pyrenoidosa, young barley and fruit peel polyphenols in rat breast cancer model - the effects on plasma lipid metabolism
Popis výsledku anglicky
On the basis of several preclinical and clinical studies, we have assumed that phytochemicals may play an important role in plasma lipid metabolism. The aim of this study was to evaluate the effects of dietary administered Chlorella pyrenoidosa, young barley and fruit peel polyphenols from Flavin7 on plasma lipid metabolism in breast cancer model in female rats. The phytopharmaceuticals were dietary administered at two different concentrations (0.3% and 3%). The administration of drugs lasted for the whole duration of the experiment (14-15 weeks) until autopsy. At the end of the experiments blood was collected from animals and serum lipid parameters were evaluated. Flavin7 in lower dose significantly decreased LDL-cholesterol and in higher dose significantly decreased triacylglycerol and VLDL-cholesterol levels. Chlorella at the higher dose significantly decreased LDL-and VLDL-cholesterol and triacylglycerol levels. Young barley significantly decreased LDL cholesterol (at the higher do
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
EB - Genetika a molekulární biologie
OECD FORD obor
—
Návaznosti výsledku
Projekt
<a href="/cs/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: Fakultní nemocnice u sv. Anny v Brně - Mezinárodní centrum klinického výzkumu (FNUSA - ICRC)</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Biologia
ISSN
0006-3088
e-ISSN
—
Svazek periodika
70
Číslo periodika v rámci svazku
2
Stát vydavatele periodika
SK - Slovenská republika
Počet stran výsledku
5
Strana od-do
268-272
Kód UT WoS článku
000351932000014
EID výsledku v databázi Scopus
—