Hypertension is associated with dysfunction of both peripheral and central auditory system

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F16%3A00065519" target="_blank" >RIV/00159816:_____/16:00065519 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1097/HJH.0000000000000803" target="_blank" >http://dx.doi.org/10.1097/HJH.0000000000000803</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/HJH.0000000000000803" target="_blank" >10.1097/HJH.0000000000000803</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Hypertension is associated with dysfunction of both peripheral and central auditory system

Popis výsledku v původním jazyce

Objectives:Arterial hypertension negatively influences the peripheral auditory system, causing sensorineural hearing loss. Much less is known about the detrimental effects of hypertension on the central auditory functions.Methods:We tested 32 arterial hypertension patients and 32 age and sex-matched healthy volunteers with the expanded tonal audiometry (0.125-12.5kHz), distortion product otoacoustic emissions (0.75-8kHz), horizontal minimum audible angle test for eight azimuths with binaural stimulation and the random gap detection test.Results:Peripheral hearing of the hypertensive patients was impaired in comparison with the controls within all audiometric frequencies (0.125-12.5kHz) and within specific groups of frequencies. Distortion product otoacoustic emission results were significantly lower for frequencies 4 (P=0.04) and 6kHz (P<0.001). The sound localization ability in the horizontal minimum audible angle test was significantly worse in the hypertensive patients in the 0 degrees, 45 degrees, 90 degrees, 135 degrees, and 270 degrees azimuth when the interaural pure tone average (0.5-1-2kHz) was set less than 20dB hearing level (P<0.05), and in the 0 degrees, 90 degrees, 225 degrees, and 270 degrees azimuth when the binaural pure tone average (0.5-1-2kHz) was set 20dB or less hearing level (P<0.05). Gap detection thresholds in the random gap detection test did not differ between the two groups.Conclusion:Arterial hypertension is independently related to the damage of the peripheral part of the auditory system resulting in high-frequency hearing loss. Hypertensive disturbances of central auditory processing are more discrete and concern the spatial hearing resolution.

Název v anglickém jazyce

Hypertension is associated with dysfunction of both peripheral and central auditory system

Popis výsledku anglicky

Objectives:Arterial hypertension negatively influences the peripheral auditory system, causing sensorineural hearing loss. Much less is known about the detrimental effects of hypertension on the central auditory functions.Methods:We tested 32 arterial hypertension patients and 32 age and sex-matched healthy volunteers with the expanded tonal audiometry (0.125-12.5kHz), distortion product otoacoustic emissions (0.75-8kHz), horizontal minimum audible angle test for eight azimuths with binaural stimulation and the random gap detection test.Results:Peripheral hearing of the hypertensive patients was impaired in comparison with the controls within all audiometric frequencies (0.125-12.5kHz) and within specific groups of frequencies. Distortion product otoacoustic emission results were significantly lower for frequencies 4 (P=0.04) and 6kHz (P<0.001). The sound localization ability in the horizontal minimum audible angle test was significantly worse in the hypertensive patients in the 0 degrees, 45 degrees, 90 degrees, 135 degrees, and 270 degrees azimuth when the interaural pure tone average (0.5-1-2kHz) was set less than 20dB hearing level (P<0.05), and in the 0 degrees, 90 degrees, 225 degrees, and 270 degrees azimuth when the binaural pure tone average (0.5-1-2kHz) was set 20dB or less hearing level (P<0.05). Gap detection thresholds in the random gap detection test did not differ between the two groups.Conclusion:Arterial hypertension is independently related to the damage of the peripheral part of the auditory system resulting in high-frequency hearing loss. Hypertensive disturbances of central auditory processing are more discrete and concern the spatial hearing resolution.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: Fakultní nemocnice u sv. Anny v Brně - Mezinárodní centrum klinického výzkumu (FNUSA - ICRC)</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Hypertension

ISSN

0263-6352

e-ISSN

—

Svazek periodika

34

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

736-744

Kód UT WoS článku

000371856900021

EID výsledku v databázi Scopus

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