Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F16%3A00065830" target="_blank" >RIV/00159816:_____/16:00065830 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/16:00091741

Výsledek na webu

<a href="http://dx.doi.org/10.4149/BLL_2016_110" target="_blank" >http://dx.doi.org/10.4149/BLL_2016_110</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/BLL_2016_110" target="_blank" >10.4149/BLL_2016_110</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study

Popis výsledku v původním jazyce

AIM AND METHODS: The aim of our study was to compare the development of echocardiographic parameters and functional status of patients with hypertrophic obstructive cardiomyopathy (HOCM) treated conservatively (n = 41) or by alcohol septal ablation (ASA; n = 39). RESULTS: Left ventricular outflow tract gradient (LVOTG) decreased in the first year by 53.7+-36.4 mmHg in ASA group versus 5.5+-47.1 mmHg in conservatively treated group (p<0.001), in the third year by 53.1+-41.4 mmHg versus 23.9+-42.7 mmHg (p = NS) and in the fifth year, the reduction of LVOTG was 52.1+-44.5 mmHg in ASA group and 3.0+-63.2 mmHg in conservatively treated group (p<0.05).Change in NYHA class in the first year was -1.1+-0.4 versus 0.1+-0.5, in the third year -1.0+-0.6 versus 0.1+-0.4 and in the fifth year -0.8+-0.5 versus 0.1+-0.4 (all p<0.001). CONCLUSION: Our results showed for the first time that decline of LVOTG after ASA creates a favorable left ventricle remodeling and leads to significant improvement of functional status of HOCM patients in comparison with conservative treatment (Tab. 3, Fig. 2, Ref. 42).

Název v anglickém jazyce

Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study

Popis výsledku anglicky

AIM AND METHODS: The aim of our study was to compare the development of echocardiographic parameters and functional status of patients with hypertrophic obstructive cardiomyopathy (HOCM) treated conservatively (n = 41) or by alcohol septal ablation (ASA; n = 39). RESULTS: Left ventricular outflow tract gradient (LVOTG) decreased in the first year by 53.7+-36.4 mmHg in ASA group versus 5.5+-47.1 mmHg in conservatively treated group (p<0.001), in the third year by 53.1+-41.4 mmHg versus 23.9+-42.7 mmHg (p = NS) and in the fifth year, the reduction of LVOTG was 52.1+-44.5 mmHg in ASA group and 3.0+-63.2 mmHg in conservatively treated group (p<0.05).Change in NYHA class in the first year was -1.1+-0.4 versus 0.1+-0.5, in the third year -1.0+-0.6 versus 0.1+-0.4 and in the fifth year -0.8+-0.5 versus 0.1+-0.4 (all p<0.001). CONCLUSION: Our results showed for the first time that decline of LVOTG after ASA creates a favorable left ventricle remodeling and leads to significant improvement of functional status of HOCM patients in comparison with conservative treatment (Tab. 3, Fig. 2, Ref. 42).

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Bratislavské Lekárske Listy

ISSN

0006-9248

e-ISSN

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Svazek periodika

117

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

9

Strana od-do

562-570

Kód UT WoS článku

000387631100003

EID výsledku v databázi Scopus

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