The Need for a Reliable Sleep EEG Biomarker
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067031" target="_blank" >RIV/00159816:_____/17:00067031 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.5664/jcsm.6608" target="_blank" >http://dx.doi.org/10.5664/jcsm.6608</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5664/jcsm.6608" target="_blank" >10.5664/jcsm.6608</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The Need for a Reliable Sleep EEG Biomarker
Popis výsledku v původním jazyce
Currently, we try to phenotype patients and characterize them with anatomical, biochemical, and functional characteristics. This is applied to normal and disordered sleep. Phenotyping disordered sleep is of particular interest for insomnia patients and patients with sleep-disordered breathing. For functions of sleep-disordered breathing, we are phenotyping patients according to their dominance of central apnea, obstructive apnea, or hypoventilation during sleep. The results may be the result of impaired respiratory control with different sensitivity to CO2 and pH changes, or anatomical preconditions with narrow and collapsible upper airways or obesity, or sleep regulation conditions with a low arousal threshold. For sleep regulation conditions, in contrast to anatomical or respiratory control conditions, we do not have good and well-qualifed biomarkers. Therefore, we need reliable sleep electroencephalogram (EEG) biomarkers
Název v anglickém jazyce
The Need for a Reliable Sleep EEG Biomarker
Popis výsledku anglicky
Currently, we try to phenotype patients and characterize them with anatomical, biochemical, and functional characteristics. This is applied to normal and disordered sleep. Phenotyping disordered sleep is of particular interest for insomnia patients and patients with sleep-disordered breathing. For functions of sleep-disordered breathing, we are phenotyping patients according to their dominance of central apnea, obstructive apnea, or hypoventilation during sleep. The results may be the result of impaired respiratory control with different sensitivity to CO2 and pH changes, or anatomical preconditions with narrow and collapsible upper airways or obesity, or sleep regulation conditions with a low arousal threshold. For sleep regulation conditions, in contrast to anatomical or respiratory control conditions, we do not have good and well-qualifed biomarkers. Therefore, we need reliable sleep electroencephalogram (EEG) biomarkers
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
—
OECD FORD obor
30103 - Neurosciences (including psychophysiology)
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2017
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů