Optical Coherence Tomography Findings in Patients With Coronary Stent Thrombosis A Report of the PRESTIGE Consortium (Prevention of Late Stent Thrombosis by an Interdisciplinary Global European Effort)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067122" target="_blank" >RIV/00159816:_____/17:00067122 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/17:00099994

Výsledek na webu

<a href="http://dx.doi.org/10.1161/CIRCULATIONAHA.117.026788" target="_blank" >http://dx.doi.org/10.1161/CIRCULATIONAHA.117.026788</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1161/CIRCULATIONAHA.117.026788" target="_blank" >10.1161/CIRCULATIONAHA.117.026788</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Optical Coherence Tomography Findings in Patients With Coronary Stent Thrombosis A Report of the PRESTIGE Consortium (Prevention of Late Stent Thrombosis by an Interdisciplinary Global European Effort)

Popis výsledku v původním jazyce

Background -Stent thrombosis (ST) is a serious complication following coronary stenting. Intravascular optical coherence tomography (OCT) may provide insights into mechanistic processes leading to ST. We performed a prospective, multicenter study to evaluate OCT findings in patients with ST. Methods -Consecutive patients presenting with ST were prospectively enrolled in a registry using a centralized telephone registration system. After angiographic confirmation of ST, OCT imaging of the culprit vessel was performed with frequency domain OCT. Clinical data were collected according to a standardized protocol. OCT acquisitions were analyzed at a core laboratory. Dominant and contributing findings were adjudicated by an imaging adjudication committee. Results -231 patients presenting with ST underwent OCT imaging; 14 (6.1%) had image quality precluding further analysis. Of the remaining patients, 62 (28.6%) and 155 (71.4%) presented with early and late/very late ST respectively. The underlying stent type was new generation drug-eluting stent in 50.3%. Mean reference vessel diameter was 2.9+-0.6 mm and mean reference vessel area was 6.8+-2.6 mm2 Stent underexpansion (stent expansion index &lt;0.8) was observed in 44.4% of patients. The predicted average probability (95% confidence interval) that any frame had uncovered (or thrombus-covered) struts was 99.3% (96.1%; 99.9%), 96.6% (92.4%; 98.5%), 34.3% (15.0%; 60.7%) and 9.6% (6.2%; 14.5%) and malapposed struts was 21.8% (8.4%; 45.6%), 8.5% (4.6%; 15.3%), 6.7% (2.5%; 16.3%) and 2.0% (1.2%; 3.3%) for acute, subacute, late and very late stent thrombosis respectively.

Název v anglickém jazyce

Optical Coherence Tomography Findings in Patients With Coronary Stent Thrombosis A Report of the PRESTIGE Consortium (Prevention of Late Stent Thrombosis by an Interdisciplinary Global European Effort)

Popis výsledku anglicky

Background -Stent thrombosis (ST) is a serious complication following coronary stenting. Intravascular optical coherence tomography (OCT) may provide insights into mechanistic processes leading to ST. We performed a prospective, multicenter study to evaluate OCT findings in patients with ST. Methods -Consecutive patients presenting with ST were prospectively enrolled in a registry using a centralized telephone registration system. After angiographic confirmation of ST, OCT imaging of the culprit vessel was performed with frequency domain OCT. Clinical data were collected according to a standardized protocol. OCT acquisitions were analyzed at a core laboratory. Dominant and contributing findings were adjudicated by an imaging adjudication committee. Results -231 patients presenting with ST underwent OCT imaging; 14 (6.1%) had image quality precluding further analysis. Of the remaining patients, 62 (28.6%) and 155 (71.4%) presented with early and late/very late ST respectively. The underlying stent type was new generation drug-eluting stent in 50.3%. Mean reference vessel diameter was 2.9+-0.6 mm and mean reference vessel area was 6.8+-2.6 mm2 Stent underexpansion (stent expansion index &lt;0.8) was observed in 44.4% of patients. The predicted average probability (95% confidence interval) that any frame had uncovered (or thrombus-covered) struts was 99.3% (96.1%; 99.9%), 96.6% (92.4%; 98.5%), 34.3% (15.0%; 60.7%) and 9.6% (6.2%; 14.5%) and malapposed struts was 21.8% (8.4%; 45.6%), 8.5% (4.6%; 15.3%), 6.7% (2.5%; 16.3%) and 2.0% (1.2%; 3.3%) for acute, subacute, late and very late stent thrombosis respectively.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Circulation

ISSN

0009-7322

e-ISSN

—

Svazek periodika

136

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

57

Strana od-do

1007

Kód UT WoS článku

000410062800007

EID výsledku v databázi Scopus

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