PET/CT imaging in polymyalgia rheumatica: praepubic F-18-FDG uptake correlates with pectineus and adductor longus muscles enthesitis and with tenosynovitis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067558" target="_blank" >RIV/00159816:_____/17:00067558 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/17:00098714 RIV/65269705:_____/17:00067558

Výsledek na webu

<a href="https://www.degruyter.com/view/j/raon.2017.51.issue-1/raon-2017-0001/raon-2017-0001.xml" target="_blank" >https://www.degruyter.com/view/j/raon.2017.51.issue-1/raon-2017-0001/raon-2017-0001.xml</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/raon-2017-0001" target="_blank" >10.1515/raon-2017-0001</a>

Jazyk výsledku

angličtina

Název v původním jazyce

PET/CT imaging in polymyalgia rheumatica: praepubic F-18-FDG uptake correlates with pectineus and adductor longus muscles enthesitis and with tenosynovitis

Popis výsledku v původním jazyce

Background. The role of F-18-fluorodeoxyglucose positron emission computed tomography (F-18-FDG PET/CT) is increasing in the diagnosis of polymyalgia rheumatica (PMR), one of the most common inflammatory rheumatic diseases. In addition to other locations, increased 18F-FDG accumulation has been detected in the praepubic region in some patients. However, a deeper description and pathophysiological explanation of this increased praepubic accumulation has been lacking. The aim of the presented study is to confirm a decrease in praepubic 18F-FDG accumulation in response to therapy and to describe potential correlations to other 18F-FDG PET/CT scan characteristics during the course of disease. As a secondary objective, we describe the pathological aspects of the observed praepubic 18F-FDG uptake. Patients and methods. A retrospective review of patients with newly suspected PMR undergoing baseline and follow up F-18-FDG PET/CT between February 2010 and March 2016 is given. Those with a visually detected presence of praepubic F-18-FDG accumulation were further analysed. The uptake was assessed visually and also semi-quantitatively in the defined region of interest by calculation of target-to-liver ratios. Other regions typical for PMR were systematically described as well (shoulders, hips, sternoclavicular joints, ischiogluteal bursae, spinous interspaces). Results. Twenty-three out of 89 screened patients (26%) presented with initial praepubic F-18-FDG PET/CT positivity, 15 of whom also underwent follow up 18F-FDG PET/CT examination. Five out of 15 patients presented with increased 18F-FDG accumulation in large arteries as a sign of giant cell arferitis. During follow up examination, decrease in 18F-FDG accumulation caused by therapeutic intervention was observed in all evaluated locations in all analysed patients and no new positivity was indicated, including periarticular, extraarticular tissues or target large vessels.

Název v anglickém jazyce

PET/CT imaging in polymyalgia rheumatica: praepubic F-18-FDG uptake correlates with pectineus and adductor longus muscles enthesitis and with tenosynovitis

Popis výsledku anglicky

Background. The role of F-18-fluorodeoxyglucose positron emission computed tomography (F-18-FDG PET/CT) is increasing in the diagnosis of polymyalgia rheumatica (PMR), one of the most common inflammatory rheumatic diseases. In addition to other locations, increased 18F-FDG accumulation has been detected in the praepubic region in some patients. However, a deeper description and pathophysiological explanation of this increased praepubic accumulation has been lacking. The aim of the presented study is to confirm a decrease in praepubic 18F-FDG accumulation in response to therapy and to describe potential correlations to other 18F-FDG PET/CT scan characteristics during the course of disease. As a secondary objective, we describe the pathological aspects of the observed praepubic 18F-FDG uptake. Patients and methods. A retrospective review of patients with newly suspected PMR undergoing baseline and follow up F-18-FDG PET/CT between February 2010 and March 2016 is given. Those with a visually detected presence of praepubic F-18-FDG accumulation were further analysed. The uptake was assessed visually and also semi-quantitatively in the defined region of interest by calculation of target-to-liver ratios. Other regions typical for PMR were systematically described as well (shoulders, hips, sternoclavicular joints, ischiogluteal bursae, spinous interspaces). Results. Twenty-three out of 89 screened patients (26%) presented with initial praepubic F-18-FDG PET/CT positivity, 15 of whom also underwent follow up 18F-FDG PET/CT examination. Five out of 15 patients presented with increased 18F-FDG accumulation in large arteries as a sign of giant cell arferitis. During follow up examination, decrease in 18F-FDG accumulation caused by therapeutic intervention was observed in all evaluated locations in all analysed patients and no new positivity was indicated, including periarticular, extraarticular tissues or target large vessels.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30224 - Radiology, nuclear medicine and medical imaging

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Radiology and Oncology

ISSN

1318-2099

e-ISSN

—

Svazek periodika

51

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

7

Strana od-do

8-14

Kód UT WoS článku

000397080400002

EID výsledku v databázi Scopus

—