Antimüllerian hormone (AMH) levels and antral follicle count (AFC) as predictors of the ovarian reaction in young healthy women

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067636" target="_blank" >RIV/00159816:_____/17:00067636 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15310/17:73586550

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Antimüllerian hormone (AMH) levels and antral follicle count (AFC) as predictors of the ovarian reaction in young healthy women

Popis výsledku v původním jazyce

Objective. To determine the predictive capacity of antimüllerian hormone (AMH) and antral follicle count (AFC) on the ovarian reserve in a population of young women who are not treated with infertility. Study design. A homogeneous collection of 61 individuals was subjected to testing by AMH, and to an ultrasound AFC test; and then was stimulated by the recombinant follicle stimulating hormone (FSH) in a dosage of 120 - 260 IU/L (mean +- standard deviation: 184.8 +- 36.36 IU/L) depending on the age and BMI. Results. The number of metaphase II oocytes (MII) retrieved was 16.8 +- 8.38 counts; the total number of retrieved oocytes (OR), i.e. the number of germinal vesicle + metaphase I + metaphase II oocytes, was 21.6 +- 10.65 counts. Linear mixed models were used to verify effects of AMH and AFC on the ovarian reaction. The results showed that the mean number of MII oocytes significantly increases by both AMH (0.6-fold; 95% confidence interval (CI): 0.05, 1.24; P=0.033) and AFC (1.3-fold; CI: 0.24, 2.45; P=0.018). The mean of OR was significantly increased by AMH (1.0-fold; CI: 0.19, 1.73; P=0.015). Conclusion. Both AFC and AMH are suitable predictors for the number of metaphase II oocytes. For predicting ovarian reserve is AMH sufficient.

Název v anglickém jazyce

Antimüllerian hormone (AMH) levels and antral follicle count (AFC) as predictors of the ovarian reaction in young healthy women

Popis výsledku anglicky

Objective. To determine the predictive capacity of antimüllerian hormone (AMH) and antral follicle count (AFC) on the ovarian reserve in a population of young women who are not treated with infertility. Study design. A homogeneous collection of 61 individuals was subjected to testing by AMH, and to an ultrasound AFC test; and then was stimulated by the recombinant follicle stimulating hormone (FSH) in a dosage of 120 - 260 IU/L (mean +- standard deviation: 184.8 +- 36.36 IU/L) depending on the age and BMI. Results. The number of metaphase II oocytes (MII) retrieved was 16.8 +- 8.38 counts; the total number of retrieved oocytes (OR), i.e. the number of germinal vesicle + metaphase I + metaphase II oocytes, was 21.6 +- 10.65 counts. Linear mixed models were used to verify effects of AMH and AFC on the ovarian reaction. The results showed that the mean number of MII oocytes significantly increases by both AMH (0.6-fold; 95% confidence interval (CI): 0.05, 1.24; P=0.033) and AFC (1.3-fold; CI: 0.24, 2.45; P=0.018). The mean of OR was significantly increased by AMH (1.0-fold; CI: 0.19, 1.73; P=0.015). Conclusion. Both AFC and AMH are suitable predictors for the number of metaphase II oocytes. For predicting ovarian reserve is AMH sufficient.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BIOMEDICAL PAPERS-OLOMOUC

ISSN

1213-8118

e-ISSN

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Svazek periodika

161

Číslo periodika v rámci svazku

S1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

4

Strana od-do

"S50"-"S53"

Kód UT WoS článku

000428945000009

EID výsledku v databázi Scopus

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