Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067763" target="_blank" >RIV/00159816:_____/17:00067763 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/17:00098829

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic

Popis výsledku v původním jazyce

Aims 1) To determine actual frequency of sensitization to the most common contact allergens present in ophtalmic products. 2) To assess clinical relevance of the results and detect sources of sensitization. Methods A total number of 1881 patients (mean age 46.5 years, 357 men, 1,524 women) with periorbital dermatitis underwent patch tested between the years 2001 and 2016 and were retrospectively enrolled into our study. Results The highest frequency of sensitization was found with thimerosal (9.7%), followed by neomycin sulfate (2.6%), benzalkonium chloride (1.3%), and parabens (0.6%). In terms of clinical relevance however the most important allergen was neomycin sulfate. Conclusion The most important allergens in ophtalmologic products in our study were neomycin sulfate followed by benzalkonium chloride. With every case of periorbital dermatitis patch tests should be considered, not only with commercial test allergens but with patient&apos;s actual ophtalmic preparations as well.

Název v anglickém jazyce

Periorbital Allergic Contact Dermatitis - The Most Common Allergens in the Czech Republic

Popis výsledku anglicky

Aims 1) To determine actual frequency of sensitization to the most common contact allergens present in ophtalmic products. 2) To assess clinical relevance of the results and detect sources of sensitization. Methods A total number of 1881 patients (mean age 46.5 years, 357 men, 1,524 women) with periorbital dermatitis underwent patch tested between the years 2001 and 2016 and were retrospectively enrolled into our study. Results The highest frequency of sensitization was found with thimerosal (9.7%), followed by neomycin sulfate (2.6%), benzalkonium chloride (1.3%), and parabens (0.6%). In terms of clinical relevance however the most important allergen was neomycin sulfate. Conclusion The most important allergens in ophtalmologic products in our study were neomycin sulfate followed by benzalkonium chloride. With every case of periorbital dermatitis patch tests should be considered, not only with commercial test allergens but with patient&apos;s actual ophtalmic preparations as well.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

30216 - Dermatology and venereal diseases

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Ophthalmology and Clinical Research

ISSN

2378-346X

e-ISSN

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Svazek periodika

4

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

074

Kód UT WoS článku

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EID výsledku v databázi Scopus

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