Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A

Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F18%3A00074110" target="_blank" >RIV/00159816:_____/18:00074110 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/68081707:_____/18:00502749 RIV/00216224:14110/18:00101364 RIV/61989592:15110/18:73590896
Výsledek na webu
<a href="https://www.sciencedirect.com/science/article/pii/S1873506118302757?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1873506118302757?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.scr.2018.11.006" target="_blank" >10.1016/j.scr.2018.11.006</a>

Jazyk výsledku
angličtina
Název v původním jazyce
Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A
Popis výsledku v původním jazyce
A human induced pluripotent stem cell line was generated from cancer-associated fibroblasts of a 68-years old patient with diagnosed prostate adenocarcinoma (PCa). The fibroblast cell line was reprogrammed with Epi5 (TM) Episomal iPSC Reprogramming Kit. Pluripotency of the derived transgene-free iPS cell line was confirmed both in vitro by detecting expression of factors of pluripotency on a single-cell level, and also in vivo using teratoma formation assay. This new iPS cell line may be used for differentiation into different prostate-specific cell types in differentiation studies.
Název v anglickém jazyce
Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A
Popis výsledku anglicky
A human induced pluripotent stem cell line was generated from cancer-associated fibroblasts of a 68-years old patient with diagnosed prostate adenocarcinoma (PCa). The fibroblast cell line was reprogrammed with Epi5 (TM) Episomal iPSC Reprogramming Kit. Pluripotency of the derived transgene-free iPS cell line was confirmed both in vitro by detecting expression of factors of pluripotency on a single-cell level, and also in vivo using teratoma formation assay. This new iPS cell line may be used for differentiation into different prostate-specific cell types in differentiation studies.

Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Projekt
<a href="/cs/project/LQ1605" target="_blank" >LQ1605: Translační medicína</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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