Impact of drugs on venous thromboembolism risk in surgical patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F19%3A00070959" target="_blank" >RIV/00159816:_____/19:00070959 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/19:00108494

Výsledek na webu

<a href="https://link.springer.com/article/10.1007%2Fs00228-019-02636-x" target="_blank" >https://link.springer.com/article/10.1007%2Fs00228-019-02636-x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00228-019-02636-x" target="_blank" >10.1007/s00228-019-02636-x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impact of drugs on venous thromboembolism risk in surgical patients

Popis výsledku v původním jazyce

PurposeThis review focuses on the most common drugs administered to surgical patients during the perioperative period that affect the risk of venous thromboembolism (VTE).ResultsAmong analgesics, the risk of VTE is increased in patients treated with diclofenac, ibuprofen, and rofecoxib, but not naproxen, while metamizole can confer a protective effect. The relationship between sedatives and VTE has not been sufficiently studied. Tricyclic antidepressants, low-potency serotonin reuptake inhibitors, and antipsychotics have been associated with increased risk of VTE. The use of diuretics in the perioperative period is poorly researched; however, hyponatremia is considered a risk factor. Other factors that may influence the risk of VTE include bridging anticoagulation, allogeneic transfusion, and hemostatic management before surgery. Pharmacotherapy for HIV or cancer may also increase VTE risk.ConclusionIncreased monitoring for VTE is therefore advisable in surgical patients and those receiving antipsychotics, antidepressants, diuretics, or analgesics.

Název v anglickém jazyce

Impact of drugs on venous thromboembolism risk in surgical patients

Popis výsledku anglicky

PurposeThis review focuses on the most common drugs administered to surgical patients during the perioperative period that affect the risk of venous thromboembolism (VTE).ResultsAmong analgesics, the risk of VTE is increased in patients treated with diclofenac, ibuprofen, and rofecoxib, but not naproxen, while metamizole can confer a protective effect. The relationship between sedatives and VTE has not been sufficiently studied. Tricyclic antidepressants, low-potency serotonin reuptake inhibitors, and antipsychotics have been associated with increased risk of VTE. The use of diuretics in the perioperative period is poorly researched; however, hyponatremia is considered a risk factor. Other factors that may influence the risk of VTE include bridging anticoagulation, allogeneic transfusion, and hemostatic management before surgery. Pharmacotherapy for HIV or cancer may also increase VTE risk.ConclusionIncreased monitoring for VTE is therefore advisable in surgical patients and those receiving antipsychotics, antidepressants, diuretics, or analgesics.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

<a href="/cs/project/NV15-33437A" target="_blank" >NV15-33437A: Vliv edukace na vybrané psychosomatické faktory u pacientů indikovaných k implantaci cévní protézy</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Clinical Pharmacology

ISSN

0031-6970

e-ISSN

—

Svazek periodika

75

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

17

Strana od-do

751-767

Kód UT WoS článku

000469367900002

EID výsledku v databázi Scopus

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