Impulsivity in patients with borderline personality disorder: a comprehensive profile compared with healthy people and patients with ADHD

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F20%3A00071910" target="_blank" >RIV/00159816:_____/20:00071910 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/20:00115115 RIV/65269705:_____/20:00071910

Výsledek na webu

<a href="https://www.cambridge.org/core/journals/psychological-medicine/article/impulsivity-in-patients-with-borderline-personality-disorder-a-comprehensive-profile-compared-with-healthy-people-and-patients-with-adhd/74FA9293042740200F0607A6C9CC1089" target="_blank" >https://www.cambridge.org/core/journals/psychological-medicine/article/impulsivity-in-patients-with-borderline-personality-disorder-a-comprehensive-profile-compared-with-healthy-people-and-patients-with-adhd/74FA9293042740200F0607A6C9CC1089</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1017/S0033291719001892" target="_blank" >10.1017/S0033291719001892</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impulsivity in patients with borderline personality disorder: a comprehensive profile compared with healthy people and patients with ADHD

Popis výsledku v původním jazyce

BACKGROUND: Impulsivity is a core symptom of borderline personality disorder (BPD). Impulsivity is a heterogeneous concept, and a comprehensive evaluation of impulsivity dimensions is lacking in the literature. Moreover, it is unclear whether BPD patients manifest impaired cognitive functioning that might be associated with impulsivity in another patient group, such as ADHD, a frequent comorbidity of BPD. METHODS: We tested 39 patients with BPD without major psychiatric comorbidities and ADHD, 25 patients with ADHD, and 55 healthy controls (HC) using a test battery consisting of a self-report measure of impulsivity (UPPS-P questionnaire), behavioral measures of impulsivity - impulsive action (Go/NoGo task, stop signal task) and impulsive choice (delay discounting task, Iowa gambling task), and standardized measures of attention (d2 test), working memory (digit span), and executive functioning (Tower of London). RESULTS: Patients with BPD and ADHD, as compared with HC, manifested increased self-reported impulsivity except sensation seeking and increased impulsive choice; patients with ADHD but not BPD showed increased impulsive action and deficits in cognitive functioning. Negative urgency was increased in BPD as compared to both HC and ADHD groups and correlated with BPD severity. CONCLUSIONS: Patients with BPD without ADHD comorbidity had increased self-reported impulsivity and impulsive choice, but intact impulsive action and cognitive functioning. Controlling for ADHD comorbidity in BPD samples is necessary. Negative urgency is the most diagnostically specific impulsivity dimension in BPD.

Název v anglickém jazyce

Impulsivity in patients with borderline personality disorder: a comprehensive profile compared with healthy people and patients with ADHD

Popis výsledku anglicky

BACKGROUND: Impulsivity is a core symptom of borderline personality disorder (BPD). Impulsivity is a heterogeneous concept, and a comprehensive evaluation of impulsivity dimensions is lacking in the literature. Moreover, it is unclear whether BPD patients manifest impaired cognitive functioning that might be associated with impulsivity in another patient group, such as ADHD, a frequent comorbidity of BPD. METHODS: We tested 39 patients with BPD without major psychiatric comorbidities and ADHD, 25 patients with ADHD, and 55 healthy controls (HC) using a test battery consisting of a self-report measure of impulsivity (UPPS-P questionnaire), behavioral measures of impulsivity - impulsive action (Go/NoGo task, stop signal task) and impulsive choice (delay discounting task, Iowa gambling task), and standardized measures of attention (d2 test), working memory (digit span), and executive functioning (Tower of London). RESULTS: Patients with BPD and ADHD, as compared with HC, manifested increased self-reported impulsivity except sensation seeking and increased impulsive choice; patients with ADHD but not BPD showed increased impulsive action and deficits in cognitive functioning. Negative urgency was increased in BPD as compared to both HC and ADHD groups and correlated with BPD severity. CONCLUSIONS: Patients with BPD without ADHD comorbidity had increased self-reported impulsivity and impulsive choice, but intact impulsive action and cognitive functioning. Controlling for ADHD comorbidity in BPD samples is necessary. Negative urgency is the most diagnostically specific impulsivity dimension in BPD.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30215 - Psychiatry

Projekt

<a href="/cs/project/NV15-30062A" target="_blank" >NV15-30062A: Fenotypy impulzivity u neuropsychiatrických poruch a jejich klinický význam</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Psychological Medicine

ISSN

0033-2917

e-ISSN

—

Svazek periodika

50

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

1829-1838

Kód UT WoS článku

000565265300006

EID výsledku v databázi Scopus

2-s2.0-85071194993