MyocardialT(1)mapping using SMART(1)Map and MOLLI mapping in asymptomatic patients with recent extracardiac sarcoidosis
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F20%3A00073093" target="_blank" >RIV/00159816:_____/20:00073093 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216224:14110/20:00116191 RIV/65269705:_____/20:00073093
Výsledek na webu
<a href="https://onlinelibrary.wiley.com/doi/10.1002/nbm.4388" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/nbm.4388</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/nbm.4388" target="_blank" >10.1002/nbm.4388</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
MyocardialT(1)mapping using SMART(1)Map and MOLLI mapping in asymptomatic patients with recent extracardiac sarcoidosis
Popis výsledku v původním jazyce
Introduction Sarcoidosis is a systemic granulomatous disease affecting in particular the respiratory tract. Cardiac magnetic resonance (CMR), including a measurement ofT(1)relaxation time, could potentially detect early stadia of sarcoidosis of the heart. The study aims to assessT(1)mapping in the detection of early cardiac involvement in asymptomatic patients with sarcoidosis. Methods One hundred and twenty patients with extracardiac sarcoidosis and without any heart disease history were included. One hundred and thirteen of them underwent a CMR examination. The mean time from the diagnosis of sarcoidosis was 0.8 (0.2-3.3) years. Cine images for the assessment of left ventricular (LV) functional parameters and pre- and post-contrast saturation method using adaptive recovery times for cardiacT(1)mapping (SMART(1)Map) and modified Look-Locker inversion recovery (MOLLI) images were acquired for the assessment of nativeT(1)relaxation time and extracellular volume (ECV). The measured parameters were compared between sarcoidosis patients and 22 controls. Results The sarcoidosis patients had normal global and regional systolic LV function-LV ejection fraction 65 +/- 5% versus 66 +/- 7% (pNS). The mean nativeT(1)relaxation times were not prolonged-1465 +/- 93 ms versus 1480 +/- 88 ms (pNS) measured by SMART(1)Map and 1317 +/- 60 ms versus 1313 +/- 83 ms (pNS) measured using a MOLLI sequence. Similarly, the mean ECV values did not increase-16.9 +/- 3.9% versus 17.9 +/- 3.7% (pNS) measured by SMART(1)Map and 30.9 +/- 2.9% versus 31.6 +/- 8.3% (pNS) measured using a MOLLI sequence. Conclusion Myocardial nativeT(1)relaxation times were not prolonged and ECV was not increased in asymptomatic patients with extracardiac sarcoidosis.
Název v anglickém jazyce
MyocardialT(1)mapping using SMART(1)Map and MOLLI mapping in asymptomatic patients with recent extracardiac sarcoidosis
Popis výsledku anglicky
Introduction Sarcoidosis is a systemic granulomatous disease affecting in particular the respiratory tract. Cardiac magnetic resonance (CMR), including a measurement ofT(1)relaxation time, could potentially detect early stadia of sarcoidosis of the heart. The study aims to assessT(1)mapping in the detection of early cardiac involvement in asymptomatic patients with sarcoidosis. Methods One hundred and twenty patients with extracardiac sarcoidosis and without any heart disease history were included. One hundred and thirteen of them underwent a CMR examination. The mean time from the diagnosis of sarcoidosis was 0.8 (0.2-3.3) years. Cine images for the assessment of left ventricular (LV) functional parameters and pre- and post-contrast saturation method using adaptive recovery times for cardiacT(1)mapping (SMART(1)Map) and modified Look-Locker inversion recovery (MOLLI) images were acquired for the assessment of nativeT(1)relaxation time and extracellular volume (ECV). The measured parameters were compared between sarcoidosis patients and 22 controls. Results The sarcoidosis patients had normal global and regional systolic LV function-LV ejection fraction 65 +/- 5% versus 66 +/- 7% (pNS). The mean nativeT(1)relaxation times were not prolonged-1465 +/- 93 ms versus 1480 +/- 88 ms (pNS) measured by SMART(1)Map and 1317 +/- 60 ms versus 1313 +/- 83 ms (pNS) measured using a MOLLI sequence. Similarly, the mean ECV values did not increase-16.9 +/- 3.9% versus 17.9 +/- 3.7% (pNS) measured by SMART(1)Map and 30.9 +/- 2.9% versus 31.6 +/- 8.3% (pNS) measured using a MOLLI sequence. Conclusion Myocardial nativeT(1)relaxation times were not prolonged and ECV was not increased in asymptomatic patients with extracardiac sarcoidosis.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10610 - Biophysics
Návaznosti výsledku
Projekt
<a href="/cs/project/LQ1605" target="_blank" >LQ1605: Translační medicína</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2020
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
NMR in biomedicine
ISSN
0952-3480
e-ISSN
—
Svazek periodika
33
Číslo periodika v rámci svazku
11
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
8
Strana od-do
"e4388"
Kód UT WoS článku
000555266900001
EID výsledku v databázi Scopus
2-s2.0-85089002383