Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F21%3A00074609" target="_blank" >RIV/00159816:_____/21:00074609 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14740/21:00120156

Výsledek na webu

<a href="https://www.hindawi.com/journals/np/2021/5594305/" target="_blank" >https://www.hindawi.com/journals/np/2021/5594305/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2021/5594305" target="_blank" >10.1155/2021/5594305</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network

Popis výsledku v původním jazyce

Many cognitive functions, including working memory, are processed within large-scale brain networks. We targeted the right frontoparietal network (FPN) with one session of transcranial direct current stimulation (tDCS) in an attempt to modulate the cognitive speed of a visual working memory task (WMT) in 27 young healthy subjects using a double-blind crossover design. We further explored the neural underpinnings of induced changes by performing resting-state fMRI prior to and immediately after each stimulation session with the main focus on the interaction between a task-positive FPN and a task-negative default mode network (DMN). Twenty minutes of 2 mA anodal tDCS was superior to sham stimulation in terms of cognitive speed manipulation of a subtask with processing of objects and tools in unconventional views (i.e., the higher cognitive load subtask of the offline WMT). This result was linked to the magnitude of resting-state functional connectivity decreases between the stimulated FPN seed and DMN seeds. We provide the first evidence for the action reappraisal mechanism of object and tool processing. Modulation of cognitive speed of the task by tDCS was reflected by FPN-DMN cross-talk changes.

Název v anglickém jazyce

Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network

Popis výsledku anglicky

Many cognitive functions, including working memory, are processed within large-scale brain networks. We targeted the right frontoparietal network (FPN) with one session of transcranial direct current stimulation (tDCS) in an attempt to modulate the cognitive speed of a visual working memory task (WMT) in 27 young healthy subjects using a double-blind crossover design. We further explored the neural underpinnings of induced changes by performing resting-state fMRI prior to and immediately after each stimulation session with the main focus on the interaction between a task-positive FPN and a task-negative default mode network (DMN). Twenty minutes of 2 mA anodal tDCS was superior to sham stimulation in terms of cognitive speed manipulation of a subtask with processing of objects and tools in unconventional views (i.e., the higher cognitive load subtask of the offline WMT). This result was linked to the magnitude of resting-state functional connectivity decreases between the stimulated FPN seed and DMN seeds. We provide the first evidence for the action reappraisal mechanism of object and tool processing. Modulation of cognitive speed of the task by tDCS was reflected by FPN-DMN cross-talk changes.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neural Plasticity

ISSN

2090-5904

e-ISSN

—

Svazek periodika

2021

Číslo periodika v rámci svazku

JUL 26

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

5594305

Kód UT WoS článku

000683157900001

EID výsledku v databázi Scopus

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