Effect of fixed orthodontic appliances on gingival status and oral microbiota: a pilot study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F22%3A00076458" target="_blank" >RIV/00159816:_____/22:00076458 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/22:00127453 RIV/65269705:_____/22:00076458

Výsledek na webu

<a href="https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-022-02511-9" target="_blank" >https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-022-02511-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s12903-022-02511-9" target="_blank" >10.1186/s12903-022-02511-9</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of fixed orthodontic appliances on gingival status and oral microbiota: a pilot study

Popis výsledku v původním jazyce

Background This pilot study aimed to investigate how fixed orthodontic appliances simultaneously applied on the upper and lower arches affect the oral environment in the medium term. Methods The oral status of 30 orthodontic patients was evaluated using the number of decay-missing-filled teeth (DMFT), plaque (PI), and gingival indices (GI) before bonding of fixed orthodontic appliances (T0) and during the therapy (T1). Besides, the gingival crevicular fluid (GCF) and a dental plaque were collected. Samples were analyzed for selected Candida sp. and for 10 selected oral bacteria using mass spectroscopy and multiplex polymerase chain reaction, respectively. Results In 60% of patients, deterioration of the oral status (demonstrated by the increase in PI) was recorded (p &lt; 0.05). Moreover, the changes in PI correlated with those of GI (p &lt; 0.001). At the T1 time point, the mean representation of Actinomyces sp. in the total prokaryotic DNA in GCF and dental plaque of individual patients increased compared to T0 (p &lt; 0.05). The probability of finding any of the 7 selected periodontal bacteria combined with Candida sp. was 10 times higher in patients in whom PI deteriorated between T0 and T1 (p &lt; 0.01). Conclusions Changes in the oral microbial diversity and an increase in PI were observed in the medium term after bonding of orthodontic appliance. Our study highlights the importance of a complex approach in this type of research as the association between clinical characteristics and combined microbial parameters is higher than when evaluated separately.

Název v anglickém jazyce

Effect of fixed orthodontic appliances on gingival status and oral microbiota: a pilot study

Popis výsledku anglicky

Background This pilot study aimed to investigate how fixed orthodontic appliances simultaneously applied on the upper and lower arches affect the oral environment in the medium term. Methods The oral status of 30 orthodontic patients was evaluated using the number of decay-missing-filled teeth (DMFT), plaque (PI), and gingival indices (GI) before bonding of fixed orthodontic appliances (T0) and during the therapy (T1). Besides, the gingival crevicular fluid (GCF) and a dental plaque were collected. Samples were analyzed for selected Candida sp. and for 10 selected oral bacteria using mass spectroscopy and multiplex polymerase chain reaction, respectively. Results In 60% of patients, deterioration of the oral status (demonstrated by the increase in PI) was recorded (p &lt; 0.05). Moreover, the changes in PI correlated with those of GI (p &lt; 0.001). At the T1 time point, the mean representation of Actinomyces sp. in the total prokaryotic DNA in GCF and dental plaque of individual patients increased compared to T0 (p &lt; 0.05). The probability of finding any of the 7 selected periodontal bacteria combined with Candida sp. was 10 times higher in patients in whom PI deteriorated between T0 and T1 (p &lt; 0.01). Conclusions Changes in the oral microbial diversity and an increase in PI were observed in the medium term after bonding of orthodontic appliance. Our study highlights the importance of a complex approach in this type of research as the association between clinical characteristics and combined microbial parameters is higher than when evaluated separately.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30208 - Dentistry, oral surgery and medicine

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BMC Oral Health

ISSN

1472-6831

e-ISSN

1472-6831

Svazek periodika

22

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

12

Strana od-do

455

Kód UT WoS článku

000874909300001

EID výsledku v databázi Scopus

2-s2.0-85140640673