Importance of evaluation of bone invasion type in squamous cell carcinomas of the oral cavity and oropharynx

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F23%3A00075809" target="_blank" >RIV/00159816:_____/23:00075809 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/23:00129952 RIV/61989592:15110/23:73612540 RIV/00098892:_____/23:10157727

Výsledek na webu

<a href="https://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-3084" target="_blank" >https://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-3084</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2021.062" target="_blank" >10.5507/bp.2021.062</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Importance of evaluation of bone invasion type in squamous cell carcinomas of the oral cavity and oropharynx

Popis výsledku v původním jazyce

Aims. The objective of this study was to compare bone invasion type with histopathological, clinical and immunohis Methods. The study included 49 patients who were treated for oral squamous cell carcinoma. Of which, 30 patients, with presence of bone invasion on histopathology, were divided according to the type of bone invasion (erosive, infiltrative, mixed). Each invasion type was compared to microvascular density using the CD34 marker. Results. The bone invasion was observed in 30 out of 49 patients (61.22%). On McNemar&apos;s test, statistically significant association was observed between bone invasion types and histopathological grade. In contrast, no significant correlation was observed between bone invasion type, and tumour volume or nodal metastases. In tumours with bone invasion of the infiltrative type, higher frequency of locoregional relapses was observed. The 5-year survival, since diagnosis, was approximately 60% in the erosive group, 40% in the mixed group, and merely 15% in the infiltrative group. Conclusion. Peritumoural microvascular density was not significantly related to bone invasion types. Whereas, a significantly higher intratumoural microvascular density was observed in infiltrative type of the bone invasion, when compared to the erosive and mixed type.

Název v anglickém jazyce

Importance of evaluation of bone invasion type in squamous cell carcinomas of the oral cavity and oropharynx

Popis výsledku anglicky

Aims. The objective of this study was to compare bone invasion type with histopathological, clinical and immunohis Methods. The study included 49 patients who were treated for oral squamous cell carcinoma. Of which, 30 patients, with presence of bone invasion on histopathology, were divided according to the type of bone invasion (erosive, infiltrative, mixed). Each invasion type was compared to microvascular density using the CD34 marker. Results. The bone invasion was observed in 30 out of 49 patients (61.22%). On McNemar&apos;s test, statistically significant association was observed between bone invasion types and histopathological grade. In contrast, no significant correlation was observed between bone invasion type, and tumour volume or nodal metastases. In tumours with bone invasion of the infiltrative type, higher frequency of locoregional relapses was observed. The 5-year survival, since diagnosis, was approximately 60% in the erosive group, 40% in the mixed group, and merely 15% in the infiltrative group. Conclusion. Peritumoural microvascular density was not significantly related to bone invasion types. Whereas, a significantly higher intratumoural microvascular density was observed in infiltrative type of the bone invasion, when compared to the erosive and mixed type.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30100 - Basic medicine

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical papers

ISSN

1213-8118

e-ISSN

1804-7521

Svazek periodika

167

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

139-144

Kód UT WoS článku

000731344000001

EID výsledku v databázi Scopus

2-s2.0-85162843197