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Prognostic value of Doppler echocardiographic coronary flow velocity assessment at rest in elderly patients

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F23%3A00079658" target="_blank" >RIV/00159816:_____/23:00079658 - isvavai.cz</a>

  • Nalezeny alternativní kódy

    RIV/00216224:14110/23:00130228

  • Výsledek na webu

    <a href="https://www.tandfonline.com/doi/full/10.1080/00015385.2022.2121538" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/00015385.2022.2121538</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/00015385.2022.2121538" target="_blank" >10.1080/00015385.2022.2121538</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    Prognostic value of Doppler echocardiographic coronary flow velocity assessment at rest in elderly patients

  • Popis výsledku v původním jazyce

    Background Atherosclerosis and coronary artery disease (CAD) are a common condition and cause of death in the elderly population. There are difficulties with risk assessment in the elderly as the objectification of their symptomatic status can be challenging due to neuromuscular weakness, physical deconditioning or neurological, orthopaedic, peripheral vascular, or respiratory limitations. Non-invasive coronary artery velocity assessment by Doppler method at rest could be helpful in the elderly population. To evaluate the prognostic role of coronary artery ultrasound assessment in a non-selected elderly population in everyday clinical practice. Methods One hundred forty-five patients, aged &gt;= 75years (99 women; 80 +/- 4 years), formed the study group. Left coronary artery flows were scanned in addition to conventional echocardiography. During a median follow-up of 26 months, 16 deaths and 2 non-fatal MI occurred. Results In multivariable analysis, maximal coronary velocity was the only independent predictor for mortality (heart rate [HR]: 1.02, 95%, CI: 1.01-1.04, p &lt; .0005) and for mortality/MI (HR: 1.02, 95%, CI: 1.01-1.03, p &lt; .0001). The value of 110 cm/s maximal coronary flow velocity (CFL) in the proximal segments of left arteries was the best predictor for death, sensitivity 50%, specificity 90%, p &lt; .005. The annual mortality rate was 16.6% persons/year for patients with elevated CFL &gt;= 110 cm/s. The value 81 cm/s was the best predictor for death/MI, sensitivity 61%, specificity 80%, p &lt; .0005; annual mortality rate was 11.2% persons/year for patients with elevated CFL &gt;= 81 cm/s (p &lt; .0001). Conclusion Doppler CFL scanning during routine echocardiography is a feasible and valuable tool for assessment of short-term prognosis in elderly patients.

  • Název v anglickém jazyce

    Prognostic value of Doppler echocardiographic coronary flow velocity assessment at rest in elderly patients

  • Popis výsledku anglicky

    Background Atherosclerosis and coronary artery disease (CAD) are a common condition and cause of death in the elderly population. There are difficulties with risk assessment in the elderly as the objectification of their symptomatic status can be challenging due to neuromuscular weakness, physical deconditioning or neurological, orthopaedic, peripheral vascular, or respiratory limitations. Non-invasive coronary artery velocity assessment by Doppler method at rest could be helpful in the elderly population. To evaluate the prognostic role of coronary artery ultrasound assessment in a non-selected elderly population in everyday clinical practice. Methods One hundred forty-five patients, aged &gt;= 75years (99 women; 80 +/- 4 years), formed the study group. Left coronary artery flows were scanned in addition to conventional echocardiography. During a median follow-up of 26 months, 16 deaths and 2 non-fatal MI occurred. Results In multivariable analysis, maximal coronary velocity was the only independent predictor for mortality (heart rate [HR]: 1.02, 95%, CI: 1.01-1.04, p &lt; .0005) and for mortality/MI (HR: 1.02, 95%, CI: 1.01-1.03, p &lt; .0001). The value of 110 cm/s maximal coronary flow velocity (CFL) in the proximal segments of left arteries was the best predictor for death, sensitivity 50%, specificity 90%, p &lt; .005. The annual mortality rate was 16.6% persons/year for patients with elevated CFL &gt;= 110 cm/s. The value 81 cm/s was the best predictor for death/MI, sensitivity 61%, specificity 80%, p &lt; .0005; annual mortality rate was 11.2% persons/year for patients with elevated CFL &gt;= 81 cm/s (p &lt; .0001). Conclusion Doppler CFL scanning during routine echocardiography is a feasible and valuable tool for assessment of short-term prognosis in elderly patients.

Klasifikace

  • Druh

    J<sub>imp</sub> - Článek v periodiku v databázi Web of Science

  • CEP obor

  • OECD FORD obor

    30201 - Cardiac and Cardiovascular systems

Návaznosti výsledku

  • Projekt

  • Návaznosti

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Ostatní

  • Rok uplatnění

    2023

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název periodika

    Acta Cardiologica

  • ISSN

    0001-5385

  • e-ISSN

    1784-973X

  • Svazek periodika

    78

  • Číslo periodika v rámci svazku

    4

  • Stát vydavatele periodika

    BE - Belgické království

  • Počet stran výsledku

    8

  • Strana od-do

    409-416

  • Kód UT WoS článku

    000863716700001

  • EID výsledku v databázi Scopus