ASO Author Reflections: The Effect of Local Adjuvants on Cortical Bone Following Intralesional Curettage of Bone Tumors

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F24%3A00081407" target="_blank" >RIV/00159816:_____/24:00081407 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/24:00136367

Výsledek na webu

<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC11300529/" target="_blank" >https://pmc.ncbi.nlm.nih.gov/articles/PMC11300529/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1245/s10434-024-15473-9" target="_blank" >10.1245/s10434-024-15473-9</a>

Jazyk výsledku

angličtina

Název v původním jazyce

ASO Author Reflections: The Effect of Local Adjuvants on Cortical Bone Following Intralesional Curettage of Bone Tumors

Popis výsledku v původním jazyce

The irregular shape of the tumor cavity in certain types of tumors poses a significant challenge in completely removing both microscopic and macroscopic tumor residues. Consequently, higher rates of local recurrence following tumor curettage have been recorded. To lower those rates, curettage should be supplemented with other local adjuvants. The objective of local adjuvant therapy is to eradicate any remaining viable tumor cells, ensuring complete removal while preserving the integrity of nearby healthy bone and surrounding soft tissue. Various treatment combinations are employed upon curettage for both benign and locally aggressive bone tumors. Despite the array of available treatment modalities, notable complication rates persisted, with postoperative fractures emerging as the most prevalent complication during follow-up periods. Thus far, no studies have comprehensively evaluated the effect of topical adjuvants on cortical bone after intralesional bone curettage by measuring density and hardness.

Název v anglickém jazyce

ASO Author Reflections: The Effect of Local Adjuvants on Cortical Bone Following Intralesional Curettage of Bone Tumors

Popis výsledku anglicky

The irregular shape of the tumor cavity in certain types of tumors poses a significant challenge in completely removing both microscopic and macroscopic tumor residues. Consequently, higher rates of local recurrence following tumor curettage have been recorded. To lower those rates, curettage should be supplemented with other local adjuvants. The objective of local adjuvant therapy is to eradicate any remaining viable tumor cells, ensuring complete removal while preserving the integrity of nearby healthy bone and surrounding soft tissue. Various treatment combinations are employed upon curettage for both benign and locally aggressive bone tumors. Despite the array of available treatment modalities, notable complication rates persisted, with postoperative fractures emerging as the most prevalent complication during follow-up periods. Thus far, no studies have comprehensively evaluated the effect of topical adjuvants on cortical bone after intralesional bone curettage by measuring density and hardness.

Druh

O - Ostatní výsledky

CEP obor

—

OECD FORD obor

30204 - Oncology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů