The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F12%3A10124604" target="_blank" >RIV/00179906:_____/12:10124604 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/12:10124604

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ajog.2012.01.004" target="_blank" >http://dx.doi.org/10.1016/j.ajog.2012.01.004</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ajog.2012.01.004" target="_blank" >10.1016/j.ajog.2012.01.004</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation

Popis výsledku v původním jazyce

The objective of the study was to determine whether the bacterial load of genital mycoplasmas and gestation age are related to intraamniotic inflammatory response using the amniotic fluid levels of 18 inflammatory mediators. STUDY DESIGN: A prospective study of 145 women with singleton pregnancies complicated by preterm prelabor rupture of membranes between 24+0 and 36+6 weeks was conducted. Amniotic fluid was obtained from all women by transabdominal amniocentesis. The amounts of genital mycoplasma deoxyribonucleic acid were determined using the threshold cycle value and relative and absolute quantification techniques. A panel of multiple proteins was analyzed simultaneously using multiplex technology. RESULTS: Twenty-four women with the presence of genital mycoplasmas in amniotic fluid were included in the final analyses. The concentrations of 9 of the 18 evaluated proteins in the amniotic fluid correlated with bacterial load of genital mycoplasmas independent of the quantification t

Název v anglickém jazyce

The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation

Popis výsledku anglicky

The objective of the study was to determine whether the bacterial load of genital mycoplasmas and gestation age are related to intraamniotic inflammatory response using the amniotic fluid levels of 18 inflammatory mediators. STUDY DESIGN: A prospective study of 145 women with singleton pregnancies complicated by preterm prelabor rupture of membranes between 24+0 and 36+6 weeks was conducted. Amniotic fluid was obtained from all women by transabdominal amniocentesis. The amounts of genital mycoplasma deoxyribonucleic acid were determined using the threshold cycle value and relative and absolute quantification techniques. A panel of multiple proteins was analyzed simultaneously using multiplex technology. RESULTS: Twenty-four women with the presence of genital mycoplasmas in amniotic fluid were included in the final analyses. The concentrations of 9 of the 18 evaluated proteins in the amniotic fluid correlated with bacterial load of genital mycoplasmas independent of the quantification t

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FK - Gynekologie a porodnictví

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

American Journal of Obstetrics and Gynecology

ISSN

0002-9378

e-ISSN

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Svazek periodika

206

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

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Kód UT WoS článku

000302266000029

EID výsledku v databázi Scopus

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