TLR2 in pleural fluid is modulated by talc particles during pleurodesis
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F12%3A10126162" target="_blank" >RIV/00179906:_____/12:10126162 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11150/12:10126162
Výsledek na webu
<a href="http://www.hindawi.com/journals/cdi/2012/158287/" target="_blank" >http://www.hindawi.com/journals/cdi/2012/158287/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2012/158287" target="_blank" >10.1155/2012/158287</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
TLR2 in pleural fluid is modulated by talc particles during pleurodesis
Popis výsledku v původním jazyce
The aim of this study was to examine the role of TLR2 molecule in pleural space during thoracoscopic talc pleurodesis period in patients with malignant pleural effusion. We analyzed TLR2 molecule in soluble form as well as on membrane of granulocytes inpleural fluid. Pleural fluid examination was done at three intervals during pleurodesis procedure: 1st - before the thoracoscopic procedure, 2nd - 2 hours after the terminating thoracoscopic procedure with talc insufflation, 3rd - 24 hours after the thoracoscopic procedure. We reported significant increase of soluble TLR2 molecule in pleural fluid effusion during talc pleurodesis from preoperative value. This increase was approximately 8-fould in the interval of 24 hours. The changes on granulocyte population were quite different. The mean fluorescent intensity of membrane TLR2 molecule examined by flow cytometry on granulocyte population significantly decreased after talc exposure with comparison to prethoracoscopic density. To estimat
Název v anglickém jazyce
TLR2 in pleural fluid is modulated by talc particles during pleurodesis
Popis výsledku anglicky
The aim of this study was to examine the role of TLR2 molecule in pleural space during thoracoscopic talc pleurodesis period in patients with malignant pleural effusion. We analyzed TLR2 molecule in soluble form as well as on membrane of granulocytes inpleural fluid. Pleural fluid examination was done at three intervals during pleurodesis procedure: 1st - before the thoracoscopic procedure, 2nd - 2 hours after the terminating thoracoscopic procedure with talc insufflation, 3rd - 24 hours after the thoracoscopic procedure. We reported significant increase of soluble TLR2 molecule in pleural fluid effusion during talc pleurodesis from preoperative value. This increase was approximately 8-fould in the interval of 24 hours. The changes on granulocyte population were quite different. The mean fluorescent intensity of membrane TLR2 molecule examined by flow cytometry on granulocyte population significantly decreased after talc exposure with comparison to prethoracoscopic density. To estimat
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FN - Epidemiologie, infekční nemoci a klinická imunologie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Clinical and Developmental Immunology
ISSN
1740-2522
e-ISSN
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Svazek periodika
2012
Číslo periodika v rámci svazku
December
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
7
Strana od-do
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Kód UT WoS článku
000312794800001
EID výsledku v databázi Scopus
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