The Impact of Combinations of Non-Steroidal Anti-Inflammatory Drugs and Anti-Hypertensive Agents on Blood Pressure

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10283747" target="_blank" >RIV/00179906:_____/14:10283747 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/14:10283747 RIV/00216208:11160/14:10283747

Výsledek na webu

<a href="http://www.advances.am.wroc.pl/pdf/2014/23/6/993.pdf" target="_blank" >http://www.advances.am.wroc.pl/pdf/2014/23/6/993.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17219/acem/37357" target="_blank" >10.17219/acem/37357</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The Impact of Combinations of Non-Steroidal Anti-Inflammatory Drugs and Anti-Hypertensive Agents on Blood Pressure

Popis výsledku v původním jazyce

Nowadays NSAIDs are the most frequently used groups of drugs, especially because of their availability. Their consumption is high among older people, who are much more sensitive to the side effects, and who are often also taking other drugs which can interact with them. Moreover, the majority of the older population is suffering from hypertension. This could well explain the commonly encountered experience of drug interaction between NSAIDs and antihypertensive drugs, which is very common in clinical practice. The severity of this drug interaction is classified as class C, with a recommendation to monitor therapy. However, even a minor long-term increase in blood pressure can significantly increase the risk of cardiovascular mortality, while mortalityrates can possibly be reduced by sufficiently effective treatment of hypertension. Therefore, in clinical practice, this type of interaction should not be overlooked as a major cause of failure of hypertension treatment in older patients,

Název v anglickém jazyce

The Impact of Combinations of Non-Steroidal Anti-Inflammatory Drugs and Anti-Hypertensive Agents on Blood Pressure

Popis výsledku anglicky

Nowadays NSAIDs are the most frequently used groups of drugs, especially because of their availability. Their consumption is high among older people, who are much more sensitive to the side effects, and who are often also taking other drugs which can interact with them. Moreover, the majority of the older population is suffering from hypertension. This could well explain the commonly encountered experience of drug interaction between NSAIDs and antihypertensive drugs, which is very common in clinical practice. The severity of this drug interaction is classified as class C, with a recommendation to monitor therapy. However, even a minor long-term increase in blood pressure can significantly increase the risk of cardiovascular mortality, while mortalityrates can possibly be reduced by sufficiently effective treatment of hypertension. Therefore, in clinical practice, this type of interaction should not be overlooked as a major cause of failure of hypertension treatment in older patients,

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Advances In Clinical And Experimental Medicine

ISSN

1899-5276

e-ISSN

—

Svazek periodika

23

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

8

Strana od-do

993-1000

Kód UT WoS článku

000351333600020

EID výsledku v databázi Scopus

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