Diagnostic and Predictive Value of Ultrasound and Isotope Thyroid Scanning, Alone and in Combination, in Infants Referred with Thyroid-Stimulating Hormone Elevation on Newborn Screening

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10286175" target="_blank" >RIV/00179906:_____/14:10286175 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jpeds.2013.11.057" target="_blank" >http://dx.doi.org/10.1016/j.jpeds.2013.11.057</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jpeds.2013.11.057" target="_blank" >10.1016/j.jpeds.2013.11.057</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Diagnostic and Predictive Value of Ultrasound and Isotope Thyroid Scanning, Alone and in Combination, in Infants Referred with Thyroid-Stimulating Hormone Elevation on Newborn Screening

Popis výsledku v původním jazyce

Objective To determine the diagnostic and predictive value of ultrasound and radioisotope scans of the thyroid, alone and in combination, during a single visit after initial referral by the screening laboratory with thyroid-stimulating hormone (TSH) elevation. Study design Retrospective blind review of ultrasound and radioisotope images followed by final diagnosis based on clinical features, biochemistry, imaging, and molecular genetic study. Results Infants (n = 97; 61 female) with median birthweight 3.38 kg (range 2.04-4.86) and gestation 40 weeks (range 33-42), underwent successful dual thyroid ultrasound and technetium-99m pertechnetate radioisotope scan in a single center. Combined scanning at the initial visit resulted in a correct final diagnosis in 79 of 97 (81%) cases. One patient was misdiagnosed initially as having athyreosis as the result of delayed radioisotope scan and the diagnosis of ectopia made later on diagnostic challenge. The specificity/sensitivity for radioisotop

Název v anglickém jazyce

Diagnostic and Predictive Value of Ultrasound and Isotope Thyroid Scanning, Alone and in Combination, in Infants Referred with Thyroid-Stimulating Hormone Elevation on Newborn Screening

Popis výsledku anglicky

Objective To determine the diagnostic and predictive value of ultrasound and radioisotope scans of the thyroid, alone and in combination, during a single visit after initial referral by the screening laboratory with thyroid-stimulating hormone (TSH) elevation. Study design Retrospective blind review of ultrasound and radioisotope images followed by final diagnosis based on clinical features, biochemistry, imaging, and molecular genetic study. Results Infants (n = 97; 61 female) with median birthweight 3.38 kg (range 2.04-4.86) and gestation 40 weeks (range 33-42), underwent successful dual thyroid ultrasound and technetium-99m pertechnetate radioisotope scan in a single center. Combined scanning at the initial visit resulted in a correct final diagnosis in 79 of 97 (81%) cases. One patient was misdiagnosed initially as having athyreosis as the result of delayed radioisotope scan and the diagnosis of ectopia made later on diagnostic challenge. The specificity/sensitivity for radioisotop

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FG - Pediatrie

OECD FORD obor

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Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Pediatrics

ISSN

0022-3476

e-ISSN

—

Svazek periodika

164

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

846-854

Kód UT WoS článku

000333258900037

EID výsledku v databázi Scopus

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