Electrophysiology and colour: a comparison of methods to evaluate inner retinal function

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F15%3A10313891" target="_blank" >RIV/00179906:_____/15:10313891 - isvavai.cz</a>

Výsledek na webu

<a href="http://link.springer.com/article/10.1007%2Fs10633-015-9512-z" target="_blank" >http://link.springer.com/article/10.1007%2Fs10633-015-9512-z</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10633-015-9512-z" target="_blank" >10.1007/s10633-015-9512-z</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Electrophysiology and colour: a comparison of methods to evaluate inner retinal function

Popis výsledku v původním jazyce

Several methods are used for the clinical examination of inner retinal function. The aims of this study were to compare four methods that can be used for the diagnosis and monitoring of the diseases diabetes and glaucoma. We examine correlations between results and determine which method is most sensitive for detecting disease. Twenty control subjects, 12 patients with early glaucoma and 8 patients with diabetes mellitus were enrolled in the study. All underwent 4 examinations: transient full-field pattern electroretinogram (PERG), multifocal pattern electroretinogram (mfPERG), chromatic contrast threshold measurements (protan and tritan) and blue-on yellow (SWAP) perimetry. For the total cohort of 40 subjects, the results show a significant correlation between the amplitudes of the PERG and those of the mfPERG, as well between the tritan contrast thresholds and the SWAP MD. Furthermore, ROC analyses reveal that colour contrast thresholds could significantly distinguish between the patient and the control group. Glaucoma patients alone could also be distinguished. We conclude that there is no large correlation between the results of methods, if differing pathways

Název v anglickém jazyce

Electrophysiology and colour: a comparison of methods to evaluate inner retinal function

Popis výsledku anglicky

Several methods are used for the clinical examination of inner retinal function. The aims of this study were to compare four methods that can be used for the diagnosis and monitoring of the diseases diabetes and glaucoma. We examine correlations between results and determine which method is most sensitive for detecting disease. Twenty control subjects, 12 patients with early glaucoma and 8 patients with diabetes mellitus were enrolled in the study. All underwent 4 examinations: transient full-field pattern electroretinogram (PERG), multifocal pattern electroretinogram (mfPERG), chromatic contrast threshold measurements (protan and tritan) and blue-on yellow (SWAP) perimetry. For the total cohort of 40 subjects, the results show a significant correlation between the amplitudes of the PERG and those of the mfPERG, as well between the tritan contrast thresholds and the SWAP MD. Furthermore, ROC analyses reveal that colour contrast thresholds could significantly distinguish between the patient and the control group. Glaucoma patients alone could also be distinguished. We conclude that there is no large correlation between the results of methods, if differing pathways

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FF - ORL, oftalmologie, stomatologie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Documenta Ophthalmologica

ISSN

0012-4486

e-ISSN

—

Svazek periodika

131

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

9

Strana od-do

159-167

Kód UT WoS článku

000365757200001

EID výsledku v databázi Scopus

2-s2.0-84948564022