Electrophysiological testing of visual function after mirror telescope implantation: a case report

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F16%3A10329107" target="_blank" >RIV/00179906:_____/16:10329107 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/16:10329107

Výsledek na webu

<a href="http://link.springer.com/article/10.1007%2Fs10633-016-9563-9" target="_blank" >http://link.springer.com/article/10.1007%2Fs10633-016-9563-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10633-016-9563-9" target="_blank" >10.1007/s10633-016-9563-9</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Electrophysiological testing of visual function after mirror telescope implantation: a case report

Popis výsledku v původním jazyce

Purpose: The implantation of an intraocular telescope increases life quality in patients with end-stage age-related macular degeneration (AMD). The present study monitored changes in electrophysiological markers of visual processing before and during seventeen months after a novel mirror telescope implantation in two patients (OV-male 90 years, MZ-female 70 years) with the final-stage form of AMD. Methods: Visual evoked potentials were recorded to high-contrast pattern-reversal (PR-VEP for check size 40' and 10'), low-contrast motion-onset stimuli (in visual periphery M-VEP M20o, and in central part M-VEP C8o), and event-related potentials (ERPs) in the oddball visual paradigm. Results: MZ's more systematic responses showed attenuation and prolongation of the M-VEP M20o and the PR-VEP 40' immediately after the telescope implantation with a slow amplitude recovery with unchanged prolonged latency. The implantation completely eradicated the M-VEP C8o without any restoration. The PR-VEP 10' were not readable. Only a part of OV's PR-VEP 40' and M-VEP M20' were of a repeatable and expected morphology. These OV's VEPs were consistent with MZ's findings. The ERPs did not show any effect of implantation in both patients. Post-implantation visual acuity and reaction time overcame the pre-implantation levels. Conclusions: The mirror telescope preserved peripheral vision in contrast to classic telescopes; however, the telescope concurrently reduced the luminance of the magnified retinal image, which was likely responsible for the prolongation of the VEP latencies.

Název v anglickém jazyce

Electrophysiological testing of visual function after mirror telescope implantation: a case report

Popis výsledku anglicky

Purpose: The implantation of an intraocular telescope increases life quality in patients with end-stage age-related macular degeneration (AMD). The present study monitored changes in electrophysiological markers of visual processing before and during seventeen months after a novel mirror telescope implantation in two patients (OV-male 90 years, MZ-female 70 years) with the final-stage form of AMD. Methods: Visual evoked potentials were recorded to high-contrast pattern-reversal (PR-VEP for check size 40' and 10'), low-contrast motion-onset stimuli (in visual periphery M-VEP M20o, and in central part M-VEP C8o), and event-related potentials (ERPs) in the oddball visual paradigm. Results: MZ's more systematic responses showed attenuation and prolongation of the M-VEP M20o and the PR-VEP 40' immediately after the telescope implantation with a slow amplitude recovery with unchanged prolonged latency. The implantation completely eradicated the M-VEP C8o without any restoration. The PR-VEP 10' were not readable. Only a part of OV's PR-VEP 40' and M-VEP M20' were of a repeatable and expected morphology. These OV's VEPs were consistent with MZ's findings. The ERPs did not show any effect of implantation in both patients. Post-implantation visual acuity and reaction time overcame the pre-implantation levels. Conclusions: The mirror telescope preserved peripheral vision in contrast to classic telescopes; however, the telescope concurrently reduced the luminance of the magnified retinal image, which was likely responsible for the prolongation of the VEP latencies.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Documenta Ophthalmologica

ISSN

0012-4486

e-ISSN

—

Svazek periodika

133

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

171-181

Kód UT WoS článku

000388974900003

EID výsledku v databázi Scopus

2-s2.0-84994726343