Female sex as a risk factor in minimally invasive direct coronary artery bypass grafting

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F19%3A10398625" target="_blank" >RIV/00179906:_____/19:10398625 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/19:10398625

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8MVT7uU.oV" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8MVT7uU.oV</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/14017431.2019.1612088" target="_blank" >10.1080/14017431.2019.1612088</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Female sex as a risk factor in minimally invasive direct coronary artery bypass grafting

Popis výsledku v původním jazyce

Objectives. Female sex has been generally accepted as a risk factor for short-term mortality and adverse events in surgical myocardial revascularization. However, there have been no data published yet about sex differences in minimally invasive settings. The aim of our study was to analyse short- and long- term outcomes of minimally invasive direct coronary artery bypass grafting (MIDCAB) in terms of sex comparison. Design. We retrospectively analysed the in-hospital data of all patients (n=384) undergoing MIDCAB at our department in years 2006-2016. Subsequently, the data were enriched by long-term outcomes from national registries. Results. There were 96 women in our group (25%). Females were significantly older (67.1 vs 63.8 years; p&lt;.01) and were more often diabetic (43.8% vs. 31.8%; p&lt;.01). Surgery time was longer in females (160 vs 155min; p=.02), and also the need for blood transfusion (19.8% vs 10.4%; p=.02) and wound complications (15.6% vs 2.4%; p&lt;.001) were more frequent in women. After multivariate analysis, the wound complications risk (p&lt;.001) and longer surgery times (p&lt;.01) remained associated with sex. All-cause in-hospital mortality (2.1% vs 0.7%; p=.26), long-term mortality (p=.73), and the risk of coronary intervention post-operatively (p=.16) were the same in both sexes. Higher incidence of cardiac cause of death in women was observed from long-term aspect (69.6% vs 38.7%; p=.01). However, after adjustment it lost its significance. Conclusions. Female sex is not connected with higher risk of mortality or other major events in MIDCAB. Wound healing complications remain the leading attribute associated with female sex.

Název v anglickém jazyce

Female sex as a risk factor in minimally invasive direct coronary artery bypass grafting

Popis výsledku anglicky

Objectives. Female sex has been generally accepted as a risk factor for short-term mortality and adverse events in surgical myocardial revascularization. However, there have been no data published yet about sex differences in minimally invasive settings. The aim of our study was to analyse short- and long- term outcomes of minimally invasive direct coronary artery bypass grafting (MIDCAB) in terms of sex comparison. Design. We retrospectively analysed the in-hospital data of all patients (n=384) undergoing MIDCAB at our department in years 2006-2016. Subsequently, the data were enriched by long-term outcomes from national registries. Results. There were 96 women in our group (25%). Females were significantly older (67.1 vs 63.8 years; p&lt;.01) and were more often diabetic (43.8% vs. 31.8%; p&lt;.01). Surgery time was longer in females (160 vs 155min; p=.02), and also the need for blood transfusion (19.8% vs 10.4%; p=.02) and wound complications (15.6% vs 2.4%; p&lt;.001) were more frequent in women. After multivariate analysis, the wound complications risk (p&lt;.001) and longer surgery times (p&lt;.01) remained associated with sex. All-cause in-hospital mortality (2.1% vs 0.7%; p=.26), long-term mortality (p=.73), and the risk of coronary intervention post-operatively (p=.16) were the same in both sexes. Higher incidence of cardiac cause of death in women was observed from long-term aspect (69.6% vs 38.7%; p=.01). However, after adjustment it lost its significance. Conclusions. Female sex is not connected with higher risk of mortality or other major events in MIDCAB. Wound healing complications remain the leading attribute associated with female sex.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Scandinavian Cardiovascular Journal

ISSN

1401-7431

e-ISSN

—

Svazek periodika

53

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

NO - Norské království

Počet stran výsledku

7

Strana od-do

141-147

Kód UT WoS článku

000476940600005

EID výsledku v databázi Scopus

2-s2.0-85065673936