Increased qualitative and quantitative requirements put on haematopoietic cell establishments as the result of the covid-19 pandemic - own experience

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F21%3A10438978" target="_blank" >RIV/00179906:_____/21:10438978 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/21:10438978

Výsledek na webu

<a href="http://dx.doi.org/10.18462/iir.cryo.2021.0043" target="_blank" >http://dx.doi.org/10.18462/iir.cryo.2021.0043</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.18462/iir.cryo.2021.0043" target="_blank" >10.18462/iir.cryo.2021.0043</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Increased qualitative and quantitative requirements put on haematopoietic cell establishments as the result of the covid-19 pandemic - own experience

Popis výsledku v původním jazyce

The haematopoietic cell establishment of the Tissue Establishment of the University Hospital Hradec Králové (EU TE Code CZ000426) has been providing cryopreserved haematopoietic progenitor cell (HPCs) concentrates for autologous transplantation for several decades. The total of 140 - 220 autologous cryopreserved HPC units per year were delivered for clinical application in the years 2015 - 2019. Cryopreservation of allogeneic HPCs was limited to rare cases, in which coordination of the HPC harvest in the donor and the preparation of the patient for transplantation was not possible. At the beginning of the COVID-19 pandemic the fluent transport of allogeneic HPC grafts in the global scale was jeopardized by restrictions of crossing the state borders. For this reason, the European Commission gave the transport of substances of human origin (SOHO) the absolute priority. In the same time the European Group for Bone Marrow and Blood Transplantation (EMBT) issued a recommendation to cryopreserve all allogeneic HPC concentrates. Cryopreservation was performed by us in 14 unrelated HPC collections, countries of origin were Czech Republic (n = 3), FRG (n = 7), Poland (n = 2), Switzerland (n = 1), Turkey (n = 1) and in 5 related HPC collections in the year 2020. All cryopreserved HPC concentrates were found suitable for clinical application and the total of 111 units were transplanted. The total number of cryopreserved HPC units transplanted in 2020 including 205 autologous ones was 316, which is approximately 200 % of the number of units transplanted in the previous year 2019.

Název v anglickém jazyce

Increased qualitative and quantitative requirements put on haematopoietic cell establishments as the result of the covid-19 pandemic - own experience

Popis výsledku anglicky

The haematopoietic cell establishment of the Tissue Establishment of the University Hospital Hradec Králové (EU TE Code CZ000426) has been providing cryopreserved haematopoietic progenitor cell (HPCs) concentrates for autologous transplantation for several decades. The total of 140 - 220 autologous cryopreserved HPC units per year were delivered for clinical application in the years 2015 - 2019. Cryopreservation of allogeneic HPCs was limited to rare cases, in which coordination of the HPC harvest in the donor and the preparation of the patient for transplantation was not possible. At the beginning of the COVID-19 pandemic the fluent transport of allogeneic HPC grafts in the global scale was jeopardized by restrictions of crossing the state borders. For this reason, the European Commission gave the transport of substances of human origin (SOHO) the absolute priority. In the same time the European Group for Bone Marrow and Blood Transplantation (EMBT) issued a recommendation to cryopreserve all allogeneic HPC concentrates. Cryopreservation was performed by us in 14 unrelated HPC collections, countries of origin were Czech Republic (n = 3), FRG (n = 7), Poland (n = 2), Switzerland (n = 1), Turkey (n = 1) and in 5 related HPC collections in the year 2020. All cryopreserved HPC concentrates were found suitable for clinical application and the total of 111 units were transplanted. The total number of cryopreserved HPC units transplanted in 2020 including 205 autologous ones was 316, which is approximately 200 % of the number of units transplanted in the previous year 2019.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

30205 - Hematology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Cryogenics 2021 online. The 16th Cryogenics 2021 IIR International Conference, October 5-7, 2021. Proceedings

ISBN

978-2-36215-047-0

ISSN

0151-1637

e-ISSN

—

Počet stran výsledku

5

Strana od-do

173-177

Název nakladatele

International Institute of Refrigeration

Místo vydání

Paris

Místo konání akce

Czech Republic

Datum konání akce

5. 10. 2021

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

001304907400022