Cognitive changes associated with cerebral emboli during coronary intervention

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F23%3A10470407" target="_blank" >RIV/00179906:_____/23:10470407 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/23:A2402NP5 RIV/00216208:11150/23:10470407 RIV/61989592:15110/23:73622802

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=JaxckHngbm" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=JaxckHngbm</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/BLL_2023_099" target="_blank" >10.4149/BLL_2023_099</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cognitive changes associated with cerebral emboli during coronary intervention

Popis výsledku v původním jazyce

OBJECTIVE: To investigate factors influencing the frequency and type of microembolic signals (MES) detected using transcranial Doppler (TCD) in patients undergoing elective coronary intervention, and to correlate MES with silent stroke detected using magnetic resonance imaging (MRI) and cognitive dysfunction. METHODS: The subset study of a randomized clinical trial was conducted on 70 patients (58 males; mean age 59.9 +/- 8.4 years) who underwent bilateral TCD monitoring of middle cerebral arteries (MCAs) during elective coronary interventions. Neurologic examination and brain MRI were performed prior to, and 24 h post-intervention. Cognitive function tests were performed prior to, and on day 30 post-intervention. RESULTS: The incidence of detected MES was 94.3 %. Eighteen (25.7 %) patients had new clinically asymptomatic ischemic lesions on MRI. The number of solid MES negatively correlated with changes in revised Addenbrooke&apos;s Cognitive Examination test (ACE-R) and, the number of solid MES and combinations of solid and gaseous MES negatively correlated with changes in Mini Mental-State Examination (MMSE) conducted on day 30 after the intervention (p &lt; 0.05 in all cases). CONCLUSION: Cardiac catheterization was associated with a high risk of cerebral embolism in our patients. A higher number of solid MES and combinations of solid and gaseous MES was associated with the deterioration in cognitive tests (Tab. 5, Fig. 3, Ref. 30). Text in PDF www.elis.sk

Název v anglickém jazyce

Cognitive changes associated with cerebral emboli during coronary intervention

Popis výsledku anglicky

OBJECTIVE: To investigate factors influencing the frequency and type of microembolic signals (MES) detected using transcranial Doppler (TCD) in patients undergoing elective coronary intervention, and to correlate MES with silent stroke detected using magnetic resonance imaging (MRI) and cognitive dysfunction. METHODS: The subset study of a randomized clinical trial was conducted on 70 patients (58 males; mean age 59.9 +/- 8.4 years) who underwent bilateral TCD monitoring of middle cerebral arteries (MCAs) during elective coronary interventions. Neurologic examination and brain MRI were performed prior to, and 24 h post-intervention. Cognitive function tests were performed prior to, and on day 30 post-intervention. RESULTS: The incidence of detected MES was 94.3 %. Eighteen (25.7 %) patients had new clinically asymptomatic ischemic lesions on MRI. The number of solid MES negatively correlated with changes in revised Addenbrooke&apos;s Cognitive Examination test (ACE-R) and, the number of solid MES and combinations of solid and gaseous MES negatively correlated with changes in Mini Mental-State Examination (MMSE) conducted on day 30 after the intervention (p &lt; 0.05 in all cases). CONCLUSION: Cardiac catheterization was associated with a high risk of cerebral embolism in our patients. A higher number of solid MES and combinations of solid and gaseous MES was associated with the deterioration in cognitive tests (Tab. 5, Fig. 3, Ref. 30). Text in PDF www.elis.sk

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

<a href="/cs/project/NU21-09-00357" target="_blank" >NU21-09-00357: Výhody fotodynamické a sonodynamické terapie u multiresistentních mikroorganismů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Bratislavské lekárske listy / Bratislava Medical Journal

ISSN

0006-9248

e-ISSN

1336-0345

Svazek periodika

124

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

8

Strana od-do

639-646

Kód UT WoS článku

001069868600002

EID výsledku v databázi Scopus

2-s2.0-85168826103